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RPS26 |
ribosomal protein S26 |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Peptide chain elongation
- SRP-dependent cotranslational protein targeting to membrane
- SRP-dependent cotranslational protein targeting to membrane
- Viral mRNA Translation
- Selenocysteine synthesis
- Major pathway of rRNA processing in the nucleolus and cytosol
- Translation initiation complex formation
- Formation of a pool of free 40S subunits
- Formation of the ternary complex, and subsequently, the 43S complex
- Ribosomal scanning and start codon recognition
- GTP hydrolysis and joining of the 60S ribosomal subunit
- Eukaryotic Translation Termination
- Regulation of expression of SLITs and ROBOs
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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- Diamond-Blackfan anemia (DBA)
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SLC25A13 |
solute carrier family 25 member 13 |
- Mitochondrial protein import
- Gluconeogenesis
- Aspartate and asparagine metabolism
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SLC9A3R1 |
SLC9A3 regulator 1 |
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- Nephrolithiasis/osteoporosis, hypophosphatemic
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SNRNP200 |
small nuclear ribonucleoprotein U5 subunit 200 |
- mRNA Splicing - Major Pathway
- mRNA Splicing - Minor Pathway
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- Retinitis pigmentosa (RP)
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SPTAN1 |
spectrin alpha, non-erythrocytic 1 |
- Caspase-mediated cleavage of cytoskeletal proteins
- Nephrin family interactions
- NCAM signaling for neurite out-growth
- NCAM signaling for neurite out-growth
- Interaction between L1 and Ankyrins
- Interaction between L1 and Ankyrins
- RAF/MAP kinase cascade
- Neutrophil degranulation
- COPI-mediated anterograde transport
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- Early infantile epileptic encephalopathy; Ohtahara syndrome
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TUFM |
Tu translation elongation factor, mitochondrial |
- Mitochondrial translation elongation
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- Zinc
- Guanosine-5'-Diphosphate
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Combined oxidative phosphorylation deficiency (COXPD)
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TWIST1 |
twist family bHLH transcription factor 1 |
- Interleukin-4 and Interleukin-13 signaling
- Transcriptional regulation by RUNX2
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
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- Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
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AATK |
apoptosis associated tyrosine kinase |
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ABCF2 |
ATP binding cassette subfamily F member 2 |
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ACTL6A |
actin like 6A |
- HATs acetylate histones
- RMTs methylate histone arginines
- UCH proteinases
- DNA Damage Recognition in GG-NER
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
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AFP |
alpha fetoprotein |
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Post-translational protein phosphorylation
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AKAP12 |
A-kinase anchoring protein 12 |
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ALYREF |
Aly/REF export factor |
- Transport of the SLBP independent Mature mRNA
- Transport of the SLBP Dependant Mature mRNA
- Transport of Mature mRNA Derived from an Intronless Transcript
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
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AMOT |
angiomotin |
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ANAPC10 |
anaphase promoting complex subunit 10 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
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ANAPC7 |
anaphase promoting complex subunit 7 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
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ANP32B |
acidic nuclear phosphoprotein 32 family member B |
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ANP32E |
acidic nuclear phosphoprotein 32 family member E |
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ANXA2 |
annexin A2 |
- Smooth Muscle Contraction
- Neutrophil degranulation
- Dissolution of Fibrin Clot
- Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
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- Tenecteplase
- Fluocinolone acetonide
- Lanoteplase
- Artenimol
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ARF4 |
ADP ribosylation factor 4 |
- VxPx cargo-targeting to cilium
- VxPx cargo-targeting to cilium
- COPI-mediated anterograde transport
- COPI-dependent Golgi-to-ER retrograde traffic
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