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NCK1 |
NCK adaptor protein 1 |
- Downstream signal transduction
- Generation of second messenger molecules
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- Nephrin family interactions
- DCC mediated attractive signaling
- DCC mediated attractive signaling
- Activation of RAC1
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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NCK2 |
NCK adaptor protein 2 |
- Downstream signal transduction
- Nephrin family interactions
- Ephrin signaling
- Activation of RAC1
- VEGFA-VEGFR2 Pathway
- Regulation of cortical dendrite branching
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NF2 |
neurofibromin 2 |
- Regulation of actin dynamics for phagocytic cup formation
- RHO GTPases activate PAKs
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- Malignant pleural mesothelioma
- Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
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PCBD2 |
pterin-4 alpha-carbinolamine dehydratase 2 |
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PLCG1 |
phospholipase C gamma 1 |
- ISG15 antiviral mechanism
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- PLCG1 events in ERBB2 signaling
- DAG and IP3 signaling
- PLC-gamma1 signalling
- Synthesis of IP3 and IP4 in the cytosol
- Downstream signal transduction
- Generation of second messenger molecules
- Role of phospholipids in phagocytosis
- Role of phospholipids in phagocytosis
- PECAM1 interactions
- EGFR interacts with phospholipase C-gamma
- DAP12 signaling
- FCERI mediated MAPK activation
- FCERI mediated Ca+2 mobilization
- FCERI mediated Ca+2 mobilization
- Role of second messengers in netrin-1 signaling
- VEGFR2 mediated cell proliferation
- VEGFR2 mediated cell proliferation
- Constitutive Signaling by EGFRvIII
- Phospholipase C-mediated cascade: FGFR1
- Phospholipase C-mediated cascade; FGFR2
- Phospholipase C-mediated cascade; FGFR3
- Phospholipase C-mediated cascade; FGFR4
- Signaling by FGFR2 in disease
- Signaling by FGFR4 in disease
- Signaling by FGFR1 in disease
- Signaling by FGFR3 point mutants in cancer
- RET signaling
- Activated NTRK2 signals through PLCG1
- Activated NTRK2 signals through PLCG1
- Erythropoietin activates Phospholipase C gamma (PLCG)
- Activated NTRK3 signals through PLCG1
- Activated NTRK3 signals through PLCG1
- FCGR3A-mediated IL10 synthesis
- Signaling by ERBB2 KD Mutants
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
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PLCG2 |
phospholipase C gamma 2 |
- GPVI-mediated activation cascade
- Toll Like Receptor 4 (TLR4) Cascade
- Synthesis of IP3 and IP4 in the cytosol
- Generation of second messenger molecules
- Role of phospholipids in phagocytosis
- DAP12 signaling
- FCERI mediated MAPK activation
- FCERI mediated Ca+2 mobilization
- FCERI mediated Ca+2 mobilization
- CLEC7A (Dectin-1) signaling
- CLEC7A (Dectin-1) signaling
- Dectin-2 family
- Dectin-2 family
- Erythropoietin activates Phospholipase C gamma (PLCG)
- FCGR3A-mediated IL10 synthesis
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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PLXNB1 |
plexin B1 |
- G alpha (12/13) signalling events
- Sema4D mediated inhibition of cell attachment and migration
- Sema4D induced cell migration and growth-cone collapse
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PTPRJ |
protein tyrosine phosphatase receptor type J |
- Phosphorylation of CD3 and TCR zeta chains
- Neutrophil degranulation
- Negative regulation of MET activity
- Negative regulation of FLT3
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RANBP10 |
RAN binding protein 10 |
- MET activates RAS signaling
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RANBP9 |
RAN binding protein 9 |
- L1CAM interactions
- RAF/MAP kinase cascade
- MET activates RAS signaling
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RASA1 |
RAS p21 protein activator 1 |
- Downstream signal transduction
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- VEGFR2 mediated cell proliferation
- Regulation of RAS by GAPs
- PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
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- RASA1-related disorders, including: Parkes-Weber slndrome; Capillary malformation-arteriovenous malformation (CM-AVM); Arteriovenous fistula (AVF)
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RASSF1 |
Ras association domain family member 1 |
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- Non-small cell lung cancer
- Bladder cancer
- Nasopharyngeal cancer
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SH2B1 |
SH2B adaptor protein 1 |
- Factors involved in megakaryocyte development and platelet production
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SH2B2 |
SH2B adaptor protein 2 |
- Regulation of KIT signaling
- Factors involved in megakaryocyte development and platelet production
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SH2D1A |
SH2 domain containing 1A |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
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- Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
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SH2D1B |
SH2 domain containing 1B |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
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SH2D2A |
SH2 domain containing 2A |
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SH2D3C |
SH2 domain containing 3C |
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SH3BP2 |
SH3 domain binding protein 2 |
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SHB |
SH2 domain containing adaptor protein B |
- VEGFA-VEGFR2 Pathway
- VEGFA-VEGFR2 Pathway
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