Search Results for: MAPK8

145 interactions involving MAPK8 - mitogen-activated protein kinase 8 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
GEMIN5 gem nuclear organelle associated protein 5
  • snRNP Assembly
GORASP2 golgi reassembly stacking protein 2
  • Golgi Cisternae Pericentriolar Stack Reorganization
ID2 inhibitor of DNA binding 2
  • NGF-stimulated transcription
MAPT microtubule associated protein tau
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Lansoprazole
  • Astemizole
  • Paclitaxel
  • Docetaxel
  • Flortaucipir F-18
  • Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
  • Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
  • Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
MBP myelin basic protein
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
PIAS2 protein inhibitor of activated STAT 2
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
PRKD1 protein kinase D1
  • Sphingolipid de novo biosynthesis
  • Bryostatin 1
  • Fostamatinib
REL REL proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • Hodgkin lymphoma
RPS6KB1 ribosomal protein S6 kinase B1
  • mTORC1-mediated signalling
SCOC short coiled-coil protein
  • Retrograde transport at the Trans-Golgi-Network
SERPINB3 serpin family B member 3
  • Neutrophil degranulation
  • D-Serine
  • Dexfosfoserine
SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase
  • RNA polymerase II transcribes snRNA genes
ZNF605 zinc finger protein 605
  • Generic Transcription Pathway
APBB2 amyloid beta precursor protein binding family B member 2
DUSP22 dual specificity phosphatase 22
ELK3 ETS transcription factor ELK3
ELK4 ETS transcription factor ELK4
  • Prostate cancer
ETV1 ETS variant transcription factor 1
  • Ewing's sarcoma
  • Prostate cancer
FAM193B family with sequence similarity 193 member B
HIVEP1 HIVEP zinc finger 1

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