Search Results for: MAPK8

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ELK3 ETS transcription factor ELK3
ELK4 ETS transcription factor ELK4
  • Prostate cancer
ELP1 elongator acetyltransferase complex subunit 1
  • HATs acetylate histones
EP300 E1A binding protein p300
  • Regulation of gene expression by Hypoxia-inducible Factor
  • RORA activates gene expression
  • Polo-like kinase mediated events
  • Pre-NOTCH Transcription and Translation
  • Pre-NOTCH Transcription and Translation
  • PPARA activates gene expression
  • PPARA activates gene expression
  • Formation of the beta-catenin:TCF transactivating complex
  • Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
  • NOTCH1 Intracellular Domain Regulates Transcription
  • NOTCH1 Intracellular Domain Regulates Transcription
  • NOTCH2 intracellular domain regulates transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
  • HATs acetylate histones
  • Attenuation phase
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • SUMOylation of transcription cofactors
  • Circadian Clock
  • B-WICH complex positively regulates rRNA expression
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • CD209 (DC-SIGN) signaling
  • Metalloprotease DUBs
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Regulation of TP53 Activity through Acetylation
  • Regulation of TP53 Activity through Methylation
  • PI5P Regulates TP53 Acetylation
  • Activation of the TFAP2 (AP-2) family of transcription factors
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • RUNX3 regulates NOTCH signaling
  • RUNX3 regulates NOTCH signaling
  • Regulation of RUNX3 expression and activity
  • RUNX3 regulates p14-ARF
  • NOTCH3 Intracellular Domain Regulates Transcription
  • NOTCH3 Intracellular Domain Regulates Transcription
  • NOTCH4 Intracellular Domain Regulates Transcription
  • Estrogen-dependent gene expression
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • TRAF3-dependent IRF activation pathway
  • TRAF6 mediated IRF7 activation
  • FOXO-mediated transcription of cell death genes
  • Transcriptional regulation of granulopoiesis
  • Transcriptional regulation of granulopoiesis
  • Regulation of FOXO transcriptional activity by acetylation
  • Regulation of FOXO transcriptional activity by acetylation
  • Rubinstein-Taybi syndrome
ETV1 ETS variant transcription factor 1
  • Ewing's sarcoma
  • Prostate cancer
FAM193B family with sequence similarity 193 member B
FZR1 fizzy and cell division cycle 20 related 1
  • Autodegradation of Cdh1 by Cdh1:APC/C
  • SCF-beta-TrCP mediated degradation of Emi1
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
  • Regulation of APC/C activators between G1/S and early anaphase
  • Phosphorylation of Emi1
  • Senescence-Associated Secretory Phenotype (SASP)
  • CDK-mediated phosphorylation and removal of Cdc6
  • Cyclin A:Cdk2-associated events at S phase entry
  • Transcriptional Regulation by VENTX
  • Aberrant regulation of mitotic exit in cancer due to RB1 defects
  • Antigen processing: Ubiquitination & Proteasome degradation
GEMIN5 gem nuclear organelle associated protein 5
  • snRNP Assembly
GFPT1 glutamine--fructose-6-phosphate transaminase 1
  • XBP1(S) activates chaperone genes
  • Defective GFPT1 causes CMSTA1
  • Synthesis of UDP-N-acetyl-glucosamine
GORASP2 golgi reassembly stacking protein 2
  • Golgi Cisternae Pericentriolar Stack Reorganization
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1
  • Nitric oxide stimulates guanylate cyclase
  • Smooth Muscle Contraction
HIVEP1 HIVEP zinc finger 1
HSF4 heat shock transcription factor 4
ID2 inhibitor of DNA binding 2
  • NGF-stimulated transcription
IL27RA interleukin 27 receptor subunit alpha
  • Interleukin-35 Signalling
  • Interleukin-27 signaling
  • Interleukin-27 signaling
IRF3 interferon regulatory factor 3
  • ISG15 antiviral mechanism
  • IRF3 mediated activation of type 1 IFN
  • IRF3 mediated activation of type 1 IFN
  • LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
  • Regulation of innate immune responses to cytosolic DNA
  • IRF3-mediated induction of type I IFN
  • Interferon gamma signaling
  • TICAM1-dependent activation of IRF3/IRF7
  • Interferon alpha/beta signaling
  • TRAF3-dependent IRF activation pathway
  • TRAF6 mediated IRF7 activation
  • Negative regulators of DDX58/IFIH1 signaling
  • Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
ITCH itchy E3 ubiquitin protein ligase
  • Downregulation of ERBB4 signaling
  • NOD1/2 Signaling Pathway
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Degradation of GLI1 by the proteasome
  • Hedgehog 'on' state
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Negative regulators of DDX58/IFIH1 signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
JKAMP JNK1/MAPK8 associated membrane protein
JUNB JunB proto-oncogene, AP-1 transcription factor subunit
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Interleukin-4 and Interleukin-13 signaling
  • NGF-stimulated transcription
  • NGF-stimulated transcription
JUND JunD proto-oncogene, AP-1 transcription factor subunit
  • Estrogen-dependent gene expression
  • NGF-stimulated transcription
  • NGF-stimulated transcription

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