Search Results for: LYN

137 interactions involving LYN - LYN proto-oncogene, Src family tyrosine kinase found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RPS6KB2 ribosomal protein S6 kinase B2
  • AKT phosphorylates targets in the nucleus
  • Constitutive Signaling by AKT1 E17K in Cancer
SH2B2 SH2B adaptor protein 2
  • Regulation of KIT signaling
  • Factors involved in megakaryocyte development and platelet production
TRIM63 tripartite motif containing 63
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Antigen processing: Ubiquitination & Proteasome degradation
TRIP10 thyroid hormone receptor interactor 10
  • Rho GTPase cycle
  • Clathrin-mediated endocytosis
CD72 CD72 molecule
  • Other semaphorin interactions
CHST15 carbohydrate sulfotransferase 15
  • Chondroitin sulfate biosynthesis
COASY Coenzyme A synthase
  • Coenzyme A biosynthesis
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
  • Inositol 1,3,4,5-Tetrakisphosphate
DOK3 docking protein 3
  • Neutrophil degranulation
FCAR Fc fragment of IgA receptor
  • Neutrophil degranulation
FCGR2B Fc fragment of IgG receptor IIb
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Etanercept
  • Human immunoglobulin G
  • Abciximab
  • Tositumomab
  • Alemtuzumab
  • Antithymocyte immunoglobulin (rabbit)
  • Palivizumab
  • Daclizumab
  • Bevacizumab
  • Sarilumab
  • Systemic lupus erythematosus
KHDRBS1 KH RNA binding domain containing, signal transduction associated 1
  • PTK6 Regulates Proteins Involved in RNA Processing
MATK megakaryocyte-associated tyrosine kinase
  • Downregulation of ERBB2 signaling
  • Fostamatinib
PILRB paired immunoglobin like type 2 receptor beta
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
RPS6KB1 ribosomal protein S6 kinase B1
  • mTORC1-mediated signalling
SKAP2 src kinase associated phosphoprotein 2
  • Signal regulatory protein family interactions
SNCA synuclein alpha
  • Amyloid fiber formation
  • Resveratrol
  • Copper
  • Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
  • Parkinson's disease (PD)
SPHK2 sphingosine kinase 2
  • Sphingolipid de novo biosynthesis
  • Opaganib
TRPV4 transient receptor potential cation channel subfamily V member 4
  • TRP channels
  • Cannabidiol
  • Butamben
  • Medical Cannabis
  • Nabiximols
  • Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
  • TRPV4-related skeletal dysplasias, including: Autosomal dominant brachyolmia; Spondylometaphyseal dysplasia, Kozlowski type (SMDK); Metatropic dysplasia; Spondyloepiphyseal dysplasia, Maroteaux type ; Parastremmatic dysplasia
  • TRPV4-related peripheral neuropathies, including: Congenital distal spinal muscular atrophy (CDSMA); Scapuloperoneal spinal muscle atrophy (SPSMA); Hereditary motor and sensory neuropathy type IIC (HMSN IIC)
  • Distal hereditary motor neuropathies (dHMN)
UHRF2 ubiquitin like with PHD and ring finger domains 2
  • SUMOylation of transcription cofactors

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