Search Results for: ESR1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
DARS1 aspartyl-tRNA synthetase 1
  • Selenoamino acid metabolism
  • Cytosolic tRNA aminoacylation
  • Aspartic acid
DBN1 drebrin 1
DDX1 DEAD-box helicase 1
  • tRNA processing in the nucleus
DDX17 DEAD-box helicase 17
  • SUMOylation of transcription cofactors
DDX3X DEAD-box helicase 3 X-linked
  • Neutrophil degranulation
DDX54 DEAD-box helicase 54
DHX9 DExH-box helicase 9
  • RIP-mediated NFkB activation via ZBP1
  • DEx/H-box helicases activate type I IFN and inflammatory cytokines production
  • mRNA Splicing - Major Pathway
DNMT3L DNA methyltransferase 3 like
  • DNA methylation
DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2
DUT deoxyuridine triphosphatase
  • Deoxyuridine-5'-Diphosphate
  • 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
EEF2 eukaryotic translation elongation factor 2
  • Peptide chain elongation
  • Peptide chain elongation
  • Uptake and function of diphtheria toxin
  • Synthesis of diphthamide-EEF2
  • Synthesis of diphthamide-EEF2
  • Neutrophil degranulation
  • Protein methylation
  • Adenosine-5-Diphosphoribose
  • Diphthamide
  • Guanosine-5'-Diphosphate
  • N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
  • Esketamine
  • Moxetumomab Pasudotox
EHMT2 euchromatic histone lysine methyltransferase 2
  • Senescence-Associated Secretory Phenotype (SASP)
  • PKMTs methylate histone lysines
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • Regulation of TP53 Activity through Methylation
  • RNA Polymerase I Transcription Initiation
  • Transcriptional Regulation by VENTX
  • Transcriptional Regulation by E2F6
EIF2S2 eukaryotic translation initiation factor 2 subunit beta
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • PERK regulates gene expression
  • PERK regulates gene expression
  • ABC-family proteins mediated transport
  • Translation initiation complex formation
  • Formation of the ternary complex, and subsequently, the 43S complex
  • Ribosomal scanning and start codon recognition
  • GTP hydrolysis and joining of the 60S ribosomal subunit
  • Recycling of eIF2:GDP
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
EIF3I eukaryotic translation initiation factor 3 subunit I
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Translation initiation complex formation
  • Formation of a pool of free 40S subunits
  • Formation of the ternary complex, and subsequently, the 43S complex
  • Ribosomal scanning and start codon recognition
  • GTP hydrolysis and joining of the 60S ribosomal subunit
EIF4A3 eukaryotic translation initiation factor 4A3
  • ISG15 antiviral mechanism
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • Deadenylation of mRNA
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
EPRS1 glutamyl-prolyl-tRNA synthetase 1
  • Selenoamino acid metabolism
  • Cytosolic tRNA aminoacylation
  • tRNA modification in the nucleus and cytosol
  • Glutamic acid
  • Proline
  • 5'-O-(L-Prolylsulfamoyl)adenosine
  • 5'-O-(L-Cysteinylsulfamoyl)adenosine
  • 5'-O-(N-(Alanyl)sulfamoyl)adenosine
EPSTI1 epithelial stromal interaction 1
ESR2 estrogen receptor 2
  • PIP3 activates AKT signaling
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • Nuclear Receptor transcription pathway
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • ESR-mediated signaling
  • Extra-nuclear estrogen signaling
  • Diethylstilbestrol
  • Conjugated estrogens
  • Progesterone
  • Raloxifene
  • Estrone
  • Tamoxifen
  • Estradiol
  • Trilostane
  • Estramustine
  • Oxybenzone
  • Genistein
  • Prasterone
  • Benzophenone
  • Phthalic Acid
  • Pyrazole
  • Para-Mercury-Benzenesulfonic Acid
  • Naringenin
  • ICI-164384
  • 5-Alpha-Androstane-3-Beta,17beta-Diol
  • 4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol
  • Quercetin
  • Afimoxifene
  • Estriol
  • Estrone sulfate
  • MF101
  • CHF 4227
  • TAS-108
  • Lasofoxifene
  • Arzoxifene
  • Bazedoxifene
  • Prinaberel
  • ERB-196
  • [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
  • 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL
  • 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
  • 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL
  • (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol
  • 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
  • 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
  • 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
  • 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
  • 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
  • (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
  • 17alpha-Estriol
  • (9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one
  • Erteberel
  • (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
  • Eugenol
  • Octocrylene
  • Enzacamene
  • Equol
  • 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
  • Estradiol acetate
  • Estradiol benzoate
  • Estradiol cypionate
  • Estradiol dienanthate
  • Estradiol valerate
  • Estriol tripropionate
  • Fluoroestradiol F-18
ESRRA estrogen related receptor alpha
  • PPARA activates gene expression
  • Transcriptional activation of mitochondrial biogenesis
  • Transcriptional activation of mitochondrial biogenesis
  • Nuclear Receptor transcription pathway
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX2 expression and activity
  • Troglitazone
  • Diethylstilbestrol
  • Genistein
  • Afimoxifene
  • beta-Naphthoflavone
  • 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE
  • Flavone
FARSA phenylalanyl-tRNA synthetase subunit alpha
  • Cytosolic tRNA aminoacylation
  • Phenylalanine

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