Search Results for: EGFR

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
H3-4 H3.4 histone
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • Condensation of Prophase Chromosomes
  • DNA Damage/Telomere Stress Induced Senescence
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
  • Meiotic recombination
  • Inhibition of DNA recombination at telomere
HBEGF heparin binding EGF like growth factor
  • Signaling by ERBB2
  • Signaling by ERBB4
  • SHC1 events in ERBB2 signaling
  • SHC1 events in ERBB2 signaling
  • PI3K events in ERBB4 signaling
  • SHC1 events in ERBB4 signaling
  • Nuclear signaling by ERBB4
  • PIP3 activates AKT signaling
  • Signaling by EGFR
  • GRB2 events in EGFR signaling
  • GAB1 signalosome
  • SHC1 events in EGFR signaling
  • EGFR downregulation
  • GRB2 events in ERBB2 signaling
  • PI3K events in ERBB2 signaling
  • EGFR interacts with phospholipase C-gamma
  • EGFR Transactivation by Gastrin
  • EGFR Transactivation by Gastrin
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • Uptake and function of diphtheria toxin
  • Inhibition of Signaling by Overexpressed EGFR
  • RAF/MAP kinase cascade
  • ERBB2 Regulates Cell Motility
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • ERBB2 Activates PTK6 Signaling
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • PTK6 promotes HIF1A stabilization
  • Downregulation of ERBB2 signaling
  • Extra-nuclear estrogen signaling
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • Signaling by ERBB2 KD Mutants
  • Signaling by ERBB2 TMD/JMD mutants
HEMGN hemogen
HEXIM1 HEXIM P-TEFb complex subunit 1
HOXC10 homeobox C10
HSH2D hematopoietic SH2 domain containing
HSPA1A heat shock protein family A (Hsp70) member 1A
  • Viral RNP Complexes in the Host Cell Nucleus
  • Regulation of HSF1-mediated heat shock response
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • Attenuation phase
  • HSF1-dependent transactivation
  • AUF1 (hnRNP D0) binds and destabilizes mRNA
  • Neutrophil degranulation
  • Regulation of HSF1-mediated heat shock response
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • Attenuation phase
  • HSF1-dependent transactivation
  • Neutrophil degranulation
ILKAP ILK associated serine/threonine phosphatase
INPPL1 inositol polyphosphate phosphatase like 1
  • Synthesis of PIPs at the plasma membrane
  • Synthesis of IP3 and IP4 in the cytosol
  • Interleukin receptor SHC signaling
IRS4 insulin receptor substrate 4
  • IRS-related events triggered by IGF1R
ITGB2 integrin subunit beta 2
  • Toll Like Receptor 4 (TLR4) Cascade
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Cell surface interactions at the vascular wall
  • Integrin cell surface interactions
  • Interleukin-4 and Interleukin-13 signaling
  • Neutrophil degranulation
  • Leukocyte adhesion deficiency (LAD), including the following four diseases: Leukocyte adhesion deficiency (I); Leukocyte adhesion deficiency (II); Leukocyte adhesion deficiency (III); LAD with Rac2 deficiency
ITSN2 intersectin 2
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
KCTD9P2 potassium channel tetramerization domain containing 9 pseudogene 2
KRT17 keratin 17
  • Keratinization
  • Formation of the cornified envelope
  • Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
KRT18 keratin 18
  • Keratinization
  • Formation of the cornified envelope
LAT linker for activation of T cells
  • GPVI-mediated activation cascade
  • Generation of second messenger molecules
LCP2 lymphocyte cytosolic protein 2
  • GPVI-mediated activation cascade
  • Generation of second messenger molecules
  • Generation of second messenger molecules
  • DAP12 signaling
  • FCERI mediated MAPK activation
  • FCERI mediated Ca+2 mobilization
  • FCERI mediated Ca+2 mobilization
LINC01139 long intergenic non-protein coding RNA 1139
LRRK1 leucine rich repeat kinase 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
  • CD28 dependent PI3K/Akt signaling
  • Dectin-1 mediated noncanonical NF-kB signaling
  • TNFR2 non-canonical NF-kB pathway
  • NIK-->noncanonical NF-kB signaling
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

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