Search Results for: EGFR

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MOB4 MOB family member 4, phocein
MT-CO2 cytochrome c oxidase subunit II
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
  • Talmapimod
MTDH metadherin
MUC1 mucin 1, cell surface associated
  • Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
  • Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
  • Defective GALNT12 causes colorectal cancer 1 (CRCS1)
  • Dectin-2 family
  • Interleukin-4 and Interleukin-13 signaling
  • O-linked glycosylation of mucins
  • Termination of O-glycan biosynthesis
  • TG4010
MUC4 mucin 4, cell surface associated
  • Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
  • Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
  • Defective GALNT12 causes colorectal cancer 1 (CRCS1)
  • Dectin-2 family
  • O-linked glycosylation of mucins
  • Termination of O-glycan biosynthesis
NANS N-acetylneuraminate synthase
  • Sialic acid metabolism
NCAM1 neural cell adhesion molecule 1
  • ECM proteoglycans
  • NCAM signaling for neurite out-growth
  • NCAM signaling for neurite out-growth
  • NCAM1 interactions
  • NCAM1 interactions
  • Signal transduction by L1
  • RAF/MAP kinase cascade
  • Interferon gamma signaling
NCK1 NCK adaptor protein 1
  • Downstream signal transduction
  • Generation of second messenger molecules
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • Nephrin family interactions
  • DCC mediated attractive signaling
  • DCC mediated attractive signaling
  • Activation of RAC1
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
NCK2 NCK adaptor protein 2
  • Downstream signal transduction
  • Nephrin family interactions
  • Ephrin signaling
  • Activation of RAC1
  • VEGFA-VEGFR2 Pathway
  • Regulation of cortical dendrite branching
NEDD4 NEDD4 E3 ubiquitin protein ligase
  • ISG15 antiviral mechanism
  • Downregulation of ERBB4 signaling
  • Regulation of PTEN localization
  • Regulation of PTEN stability and activity
  • Antigen processing: Ubiquitination & Proteasome degradation
NIBAN2 niban apoptosis regulator 2
NRG1 neuregulin 1
  • Signaling by ERBB2
  • Signaling by ERBB4
  • SHC1 events in ERBB2 signaling
  • SHC1 events in ERBB2 signaling
  • PI3K events in ERBB4 signaling
  • SHC1 events in ERBB4 signaling
  • Nuclear signaling by ERBB4
  • PIP3 activates AKT signaling
  • GRB7 events in ERBB2 signaling
  • Downregulation of ERBB2:ERBB3 signaling
  • GRB2 events in ERBB2 signaling
  • PI3K events in ERBB2 signaling
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • RAF/MAP kinase cascade
  • ERBB2 Regulates Cell Motility
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • ERBB2 Activates PTK6 Signaling
  • Downregulation of ERBB2 signaling
  • Long-term potentiation
  • Signaling by ERBB2 KD Mutants
  • Signaling by ERBB2 TMD/JMD mutants
NUMB NUMB endocytic adaptor protein
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Recycling pathway of L1
  • Degradation of GLI1 by the proteasome
  • Hedgehog 'on' state
NUMBL NUMB like endocytic adaptor protein
OAZ1 ornithine decarboxylase antizyme 1
  • Regulation of ornithine decarboxylase (ODC)
  • Ornithine
OLFM1 olfactomedin 1
PAK1 p21 (RAC1) activated kinase 1
  • Generation of second messenger molecules
  • Regulation of actin dynamics for phagocytic cup formation
  • FCERI mediated MAPK activation
  • FCERI mediated MAPK activation
  • DSCAM interactions
  • CD28 dependent Vav1 pathway
  • EPHB-mediated forward signaling
  • Ephrin signaling
  • Sema3A PAK dependent Axon repulsion
  • Activation of RAC1
  • Signal transduction by L1
  • Smooth Muscle Contraction
  • VEGFR2 mediated vascular permeability
  • CD209 (DC-SIGN) signaling
  • RHO GTPases activate PKNs
  • RHO GTPases Activate ROCKs
  • RHO GTPases activate PAKs
  • RHO GTPases activate PAKs
  • MAPK6/MAPK4 signaling
  • G beta:gamma signalling through CDC42
  • Fostamatinib
PCNA proliferating cell nuclear antigen
  • Translesion synthesis by REV1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Translesion Synthesis by POLH
  • Transcription of E2F targets under negative control by DREAM complex
  • Polymerase switching on the C-strand of the telomere
  • Processive synthesis on the C-strand of the telomere
  • Telomere C-strand (Lagging Strand) Synthesis
  • Removal of the Flap Intermediate from the C-strand
  • SUMOylation of DNA replication proteins
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • PCNA-Dependent Long Patch Base Excision Repair
  • Translesion synthesis by POLK
  • Translesion synthesis by POLI
  • Termination of translesion DNA synthesis
  • HDR through Homologous Recombination (HRR)
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Dual Incision in GG-NER
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Polymerase switching
  • Removal of the Flap Intermediate
  • Processive synthesis on the lagging strand
  • G1/S-Specific Transcription
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Liothyronine
  • Acetylsalicylic acid
PDCD6IP programmed cell death 6 interacting protein
  • Budding and maturation of HIV virion
  • Uptake and function of anthrax toxins
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
PDK3 pyruvate dehydrogenase kinase 3
  • Regulation of pyruvate dehydrogenase (PDH) complex
  • Signaling by Retinoic Acid
  • Radicicol
  • Dihydrolipoic Acid

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