Search Results for: CTNNB1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
HNF1A HNF1 homeobox A
  • Regulation of gene expression in beta cells
  • D-norleucine
  • Maturity onset diabetes of the young (MODY)
JADE1 jade family PHD finger 1
  • HATs acetylate histones
LATS2 large tumor suppressor kinase 2
  • Signaling by Hippo
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
  • Nephrin family interactions
MITF melanocyte inducing transcription factor
  • SUMOylation of transcription factors
  • Ocular albinism; Ocular albinism, type I (OA1); Waardenburg syndrome, type II (WS2-OA)
  • Waardenburg syndrome (WS)
  • Malignant melanoma
NDRG1 N-myc downstream regulated 1
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
NEURL2 neuralized E3 ubiquitin protein ligase 2
  • Neddylation
PITX2 paired like homeodomain 2
  • TFAP2 (AP-2) family regulates transcription of other transcription factors
  • Axenfeld-Rieger syndrome (ARS)
PKM pyruvate kinase M1/2
  • Neutrophil degranulation
  • Pyruvic acid
  • L-Phospholactate
  • 2-Phosphoglycolic Acid
  • 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
  • 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
  • 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
  • Copper
  • Artenimol
PTPN14 protein tyrosine phosphatase non-receptor type 14
  • Interleukin-37 signaling
  • Choanal atresia and lymphedema
PTPRK protein tyrosine phosphatase receptor type K
  • EGFR downregulation
PTPRU protein tyrosine phosphatase receptor type U
  • Signaling by SCF-KIT
PTPRZ1 protein tyrosine phosphatase receptor type Z1
  • Other interleukin signaling
RAPGEF2 Rap guanine nucleotide exchange factor 2
  • RAF/MAP kinase cascade
SALL1 spalt like transcription factor 1
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Townes-Brocks syndrome
SOX17 SRY-box transcription factor 17
  • Deactivation of the beta-catenin transactivating complex
  • Vesicoureteral reflux
TAX1BP3 Tax1 binding protein 3
  • RHO GTPases Activate Rhotekin and Rhophilins
TRIM33 tripartite motif containing 33
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
UBE3A ubiquitin protein ligase E3A
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
UHRF2 ubiquitin like with PHD and ring finger domains 2
  • SUMOylation of transcription cofactors

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