Search Results for: CTNNB1

198 interactions involving CTNNB1 - catenin beta 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
PRKCG protein kinase C gamma
  • Calmodulin induced events
  • Disinhibition of SNARE formation
  • Trafficking of GluR2-containing AMPA receptors
  • G alpha (z) signalling events
  • WNT5A-dependent internalization of FZD4
  • Response to elevated platelet cytosolic Ca2+
  • Tamoxifen
  • Fostamatinib
  • Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
PSEN2 presenilin 2
  • Nuclear signaling by ERBB4
  • Regulated proteolysis of p75NTR
  • NRIF signals cell death from the nucleus
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • NOTCH2 Activation and Transmission of Signal to the Nucleus
  • EPH-ephrin mediated repulsion of cells
  • NOTCH3 Activation and Transmission of Signal to the Nucleus
  • NOTCH4 Activation and Transmission of Signal to the Nucleus
  • Noncanonical activation of NOTCH3
  • Alzheimer's disease (AD)
PTPN14 protein tyrosine phosphatase non-receptor type 14
  • Interleukin-37 signaling
  • Choanal atresia and lymphedema
SALL1 spalt like transcription factor 1
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Townes-Brocks syndrome
SLC9A3R1 SLC9A3 regulator 1
  • Nephrolithiasis/osteoporosis, hypophosphatemic
SMAD2 SMAD family member 2
  • Signaling by NODAL
  • Signaling by NODAL
  • Signaling by Activin
  • Downregulation of TGF-beta receptor signaling
  • TGF-beta receptor signaling activates SMADs
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • SMAD2/3 Phosphorylation Motif Mutants in Cancer
  • SMAD4 MH2 Domain Mutants in Cancer
  • SMAD2/3 MH2 Domain Mutants in Cancer
  • TGFBR1 KD Mutants in Cancer
  • Transcriptional regulation of pluripotent stem cells
  • Ub-specific processing proteases
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • FOXO-mediated transcription of cell cycle genes
  • FOXO-mediated transcription of cell cycle genes
  • Dexfosfoserine
  • Colorectal cancer
SOX17 SRY-box transcription factor 17
  • Deactivation of the beta-catenin transactivating complex
  • Vesicoureteral reflux
TCF3 transcription factor 3
  • Myogenesis
  • Myogenesis
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
TCF4 transcription factor 4
  • Myogenesis
  • Myogenesis
  • Pitt-Hopkins syndrome, including: Pitt-Hopkins syndrome; Pitt-Hopkins-like syndrome
TCF7L2 transcription factor 7 like 2
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • Deactivation of the beta-catenin transactivating complex
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Ca2+ pathway
  • Binding of TCF/LEF:CTNNB1 to target gene promoters
  • Repression of WNT target genes
  • Repression of WNT target genes
  • Signaling by TCF7L2 mutants
  • Transcriptional Regulation by VENTX
  • RUNX3 regulates WNT signaling
  • Type II diabetes mellitus
TFAP2A transcription factor AP-2 alpha
  • Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • TFAP2 (AP-2) family regulates transcription of other transcription factors
  • Activation of the TFAP2 (AP-2) family of transcription factors
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
  • TFAP2 (AP-2) family regulates transcription of cell cycle factors
  • TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
  • Branchiooculofacial syndrome (BOFS)
UBE3A ubiquitin protein ligase E3A
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
ZIC3 Zic family member 3
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Transcriptional regulation of pluripotent stem cells
  • Heterotaxy; Situs ambiguus
ACP1 acid phosphatase 1
  • Adenine
  • 4-Nitrophenyl Phosphate
AJAP1 adherens junctions associated protein 1
ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1
ARHGAP32 Rho GTPase activating protein 32
  • Rho GTPase cycle
ASH2L ASH2 like, histone lysine methyltransferase complex subunit
  • Formation of the beta-catenin:TCF transactivating complex
  • PKMTs methylate histone lysines
  • Deactivation of the beta-catenin transactivating complex
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
BCL3 BCL3 transcription coactivator
BCL9 BCL9 transcription coactivator
  • Formation of the beta-catenin:TCF transactivating complex
  • Deactivation of the beta-catenin transactivating complex

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