Search Results for: CHEK2

85 interactions involving CHEK2 - checkpoint kinase 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
DAPK3 death associated protein kinase 3
  • Caspase activation via Dependence Receptors in the absence of ligand
  • 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one
  • 4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid
  • (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
  • Fostamatinib
KLK7 kallikrein related peptidase 7
  • Degradation of the extracellular matrix
  • L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide
LATS2 large tumor suppressor kinase 2
  • Signaling by Hippo
LYPD3 LY6/PLAUR domain containing 3
  • Post-translational modification: synthesis of GPI-anchored proteins
MAPT microtubule associated protein tau
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Lansoprazole
  • Astemizole
  • Paclitaxel
  • Docetaxel
  • Flortaucipir F-18
  • Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
  • Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
  • Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
NSD3 nuclear receptor binding SET domain protein 3
  • PKMTs methylate histone lysines
PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D
  • Transcriptional regulation by RUNX2
PRDM14 PR/SET domain 14
  • Transcriptional regulation of pluripotent stem cells
PSMC3IP PSMC3 interacting protein
  • Meiotic recombination
RHOBTB2 Rho related BTB domain containing 2
  • RHOBTB2 GTPase cycle
STMN1 stathmin 1
  • Nuclear signaling by ERBB4
USP39 ubiquitin specific peptidase 39
  • mRNA Splicing - Major Pathway
BAALC BAALC binder of MAP3K1 and KLF4
BEX1 brain expressed X-linked 1
DIRAS3 DIRAS family GTPase 3
FHL1 four and a half LIM domains 1
  • X-linked myopathy with postural muscle atrophy (XMPMA)
  • Reducing body myopathy (RBM)
  • Scapuloperoneal myopathy (SPM)
  • Emery-Dreifuss muscular dystrophy
FHL3 four and a half LIM domains 3
HOXC6 homeobox C6
ITIH5 inter-alpha-trypsin inhibitor heavy chain 5
KLK9 kallikrein related peptidase 9

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