Search Results for: ATXN1

292 interactions involving ATXN1 - ataxin 1 found:

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
C10orf55 chromosome 10 putative open reading frame 55
C1orf94 chromosome 1 open reading frame 94
CAMK1 calcium/calmodulin dependent protein kinase I
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Activation of RAC1 downstream of NMDARs
  • Activation of RAC1 downstream of NMDARs
  • Fostamatinib
CAMK2B calcium/calmodulin dependent protein kinase II beta
  • CaMK IV-mediated phosphorylation of CREB
  • HSF1-dependent transactivation
  • Trafficking of AMPA receptors
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
  • Ras activation upon Ca2+ influx through NMDA receptor
  • Phase 0 - rapid depolarisation
  • Ion homeostasis
  • RAF activation
  • RAF/MAP kinase cascade
  • Signaling by moderate kinase activity BRAF mutants
  • Signaling by BRAF and RAF fusions
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • Interferon gamma signaling
  • Regulation of MECP2 expression and activity
  • Ion transport by P-type ATPases
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
  • Signaling downstream of RAS mutants
  • Signaling by RAF1 mutants
  • [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile
  • Fostamatinib
CCDC136 coiled-coil domain containing 136
CCNK cyclin K
  • Formation of RNA Pol II elongation complex
  • Formation of HIV elongation complex in the absence of HIV Tat
  • HIV elongation arrest and recovery
  • Pausing and recovery of HIV elongation
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • RNA Polymerase II Pre-transcription Events
  • TP53 Regulates Transcription of DNA Repair Genes
  • RNA polymerase II transcribes snRNA genes
  • RNA polymerase II transcribes snRNA genes
  • RNA Polymerase II Transcription Elongation
CDIP1 cell death inducing p53 target 1
CDK6 cyclin dependent kinase 6
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • Oncogene Induced Senescence
  • Cyclin D associated events in G1
  • Regulation of RUNX1 Expression and Activity
  • Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
  • Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
  • Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
  • Alvocidib
  • (2S)-2-({6-[(3-Amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methyl-1-butanol
  • Fisetin
  • Palbociclib
  • Ribociclib
  • Abemaciclib
CDRT15P3 CDRT15 pseudogene 3
CFL1 cofilin 1
  • Platelet degranulation
  • Regulation of actin dynamics for phagocytic cup formation
  • EPHB-mediated forward signaling
  • Sema3A PAK dependent Axon repulsion
  • RHO GTPases Activate ROCKs
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • Dodecyldimethylamine N-oxide
  • Copper
  • Artenimol
CHRNA7 cholinergic receptor nicotinic alpha 7 subunit
  • Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
  • Choline
  • Nicotine
  • Butabarbital
  • Butalbital
  • Talbutal
  • Pentobarbital
  • Methadone
  • Secobarbital
  • Metharbital
  • Dextromethorphan
  • Thiopental
  • Mecamylamine
  • Galantamine
  • Primidone
  • Methylphenobarbital
  • Ethanol
  • Amantadine
  • Phenobarbital
  • Tubocurarine
  • Varenicline
  • Amobarbital
  • Aprobarbital
  • Butobarbital
  • Heptabarbital
  • Hexobarbital
  • Barbital
  • Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione
  • Acetylcholine
  • Lobeline
  • GTS-21
  • RPI-78M
  • Epibatidine
  • Cytisine
  • Cannabidiol
  • Encenicline
  • Choline salicylate
  • Medical Cannabis
  • Nabiximols
CIC capicua transcriptional repressor
CIRBP cold inducible RNA binding protein
CLASRP CLK4 associating serine/arginine rich protein
CLEC4F C-type lectin domain family 4 member F
COIL coilin
CPSF7 cleavage and polyadenylation specific factor 7
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
CREM cAMP responsive element modulator
CRIP2 cysteine rich protein 2
CRK CRK proto-oncogene, adaptor protein
  • ARMS-mediated activation
  • ARMS-mediated activation
  • Downstream signal transduction
  • Regulation of actin dynamics for phagocytic cup formation
  • p130Cas linkage to MAPK signaling for integrins
  • VEGFA-VEGFR2 Pathway
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • MET activates RAP1 and RAC1
  • MET receptor recycling
  • Regulation of signaling by CBL
  • FCGR3A-mediated phagocytosis

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