Search Results for: ATXN1

292 interactions involving ATXN1 - ataxin 1 found:

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel C7 complement C7
  • Terminal pathway of complement
  • Regulation of Complement cascade
  • Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
Novel CNOT6L CCR4-NOT transcription complex subunit 6 like
  • Deadenylation of mRNA
  • TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Novel PITX3 paired like homeodomain 3
Novel RPL19 ribosomal protein L19
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Peptide chain elongation
  • SRP-dependent cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane
  • Viral mRNA Translation
  • Selenocysteine synthesis
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Formation of a pool of free 40S subunits
  • GTP hydrolysis and joining of the 60S ribosomal subunit
  • Eukaryotic Translation Termination
  • Regulation of expression of SLITs and ROBOs
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
  • (S)-3-phenyllactic acid
  • Anisomycin
  • Puromycin
Novel XPO7 exportin 7
- uncharacterized LOC401442
ACACA acetyl-CoA carboxylase alpha
  • ChREBP activates metabolic gene expression
  • Biotin transport and metabolism
  • Carnitine metabolism
  • Activation of gene expression by SREBF (SREBP)
  • Defective HLCS causes multiple carboxylase deficiency
  • Fatty acyl-CoA biosynthesis
  • Biotin
ACOT7 acyl-CoA thioesterase 7
  • Mitochondrial Fatty Acid Beta-Oxidation
ADAM15 ADAM metallopeptidase domain 15
  • Degradation of the extracellular matrix
  • Invadopodia formation
ADCY6 adenylate cyclase 6
  • Glucagon signaling in metabolic regulation
  • PKA activation
  • PKA activation in glucagon signalling
  • Adenylate cyclase activating pathway
  • Adenylate cyclase inhibitory pathway
  • Adenylate cyclase inhibitory pathway
  • Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
  • Adrenaline,noradrenaline inhibits insulin secretion
  • G alpha (s) signalling events
  • G alpha (s) signalling events
  • G alpha (i) signalling events
  • G alpha (z) signalling events
  • G alpha (z) signalling events
  • Vasopressin regulates renal water homeostasis via Aquaporins
  • Hedgehog 'off' state
  • ADORA2B mediated anti-inflammatory cytokines production
  • ADORA2B mediated anti-inflammatory cytokines production
  • FCGR3A-mediated IL10 synthesis
ADD3 adducin 3
  • Miscellaneous transport and binding events
AHDC1 AT-hook DNA binding motif containing 1
AKT1 AKT serine/threonine kinase 1
  • Activation of BAD and translocation to mitochondria
  • PIP3 activates AKT signaling
  • PIP3 activates AKT signaling
  • Downregulation of ERBB2:ERBB3 signaling
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
  • MTOR signalling
  • AKT phosphorylates targets in the cytosol
  • AKT phosphorylates targets in the cytosol
  • AKT phosphorylates targets in the nucleus
  • Negative regulation of the PI3K/AKT network
  • eNOS activation
  • AKT-mediated inactivation of FOXO1A
  • Integrin signaling
  • Deactivation of the beta-catenin transactivating complex
  • CD28 dependent PI3K/Akt signaling
  • CTLA4 inhibitory signaling
  • G beta:gamma signalling through PI3Kgamma
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • VEGFR2 mediated vascular permeability
  • TP53 Regulates Metabolic Genes
  • Constitutive Signaling by AKT1 E17K in Cancer
  • Interleukin-4 and Interleukin-13 signaling
  • Regulation of TP53 Degradation
  • Regulation of TP53 Activity through Acetylation
  • Regulation of TP53 Activity through Association with Co-factors
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Cyclin E associated events during G1/S transition
  • Cyclin A:Cdk2-associated events at S phase entry
  • PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
  • RAB GEFs exchange GTP for GDP on RABs
  • RUNX2 regulates genes involved in cell migration
  • Regulation of PTEN stability and activity
  • Extra-nuclear estrogen signaling
  • Negative regulation of NOTCH4 signaling
  • FLT3 Signaling
  • Regulation of localization of FOXO transcription factors
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • ATP
  • Arsenic trioxide
  • Genistein
  • Inositol 1,3,4,5-Tetrakisphosphate
  • Resveratrol
  • Archexin
  • Enzastaurin
  • Perifosine
  • N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
  • PTEN hamartoma tumor syndrome (PHTS), including: Cowden syndrome; Bannayan-Riley-Ruvalcaba syndrome; Proteus syndrome; Proteus-like syndrome
ANKHD1 ankyrin repeat and KH domain containing 1
ANP32A acidic nuclear phosphoprotein 32 family member A
  • HuR (ELAVL1) binds and stabilizes mRNA
APBB1 amyloid beta precursor protein binding family B member 1
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
ARHGAP32 Rho GTPase activating protein 32
  • Rho GTPase cycle
ARID5A AT-rich interaction domain 5A
ASNS asparagine synthetase (glutamine-hydrolyzing)
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • Aspartate and asparagine metabolism
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
  • Aspartic acid
  • Glutamic acid
  • ATP
  • Asparagine
ATF5 activating transcription factor 5
  • Response of EIF2AK1 (HRI) to heme deficiency
  • Pseudoephedrine

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