Search Results for: AR

265 interactions involving AR - androgen receptor found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
POU2F2 POU class 2 homeobox 2
  • RNA polymerase II transcribes snRNA genes
  • RNA polymerase II transcribes snRNA genes
POU5F1 POU class 5 homeobox 1
  • POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Transcriptional regulation of pluripotent stem cells
PRKG1 protein kinase cGMP-dependent 1
  • Ca2+ pathway
PRPF6 pre-mRNA processing factor 6
  • mRNA Splicing - Major Pathway
  • mRNA Splicing - Minor Pathway
PSMC3IP PSMC3 interacting protein
  • Meiotic recombination
PXN paxillin
  • GAB1 signalosome
  • VEGFA-VEGFR2 Pathway
  • Smooth Muscle Contraction
  • Localization of the PINCH-ILK-PARVIN complex to focal adhesions
  • Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
RAC3 Rac family small GTPase 3
  • Rho GTPase cycle
  • PCP/CE pathway
RAD54L2 RAD54 like 2
RAD9A RAD9 checkpoint clamp component A
  • Activation of ATR in response to replication stress
  • HDR through Single Strand Annealing (SSA)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Regulation of TP53 Activity through Phosphorylation
  • G2/M DNA damage checkpoint
RANBP9 RAN binding protein 9
  • L1CAM interactions
  • RAF/MAP kinase cascade
  • MET activates RAS signaling
RASA1 RAS p21 protein activator 1
  • Downstream signal transduction
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • VEGFR2 mediated cell proliferation
  • Regulation of RAS by GAPs
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • RASA1-related disorders, including: Parkes-Weber slndrome; Capillary malformation-arteriovenous malformation (CM-AVM); Arteriovenous fistula (AVF)
RBAK RB associated KRAB zinc finger
RCHY1 ring finger and CHY zinc finger domain containing 1
  • Translesion Synthesis by POLH
  • Antigen processing: Ubiquitination & Proteasome degradation
REL REL proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • Hodgkin lymphoma
REPS2 RALBP1 associated Eps domain containing 2
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
RNASEL ribonuclease L
  • OAS antiviral response
  • Interferon alpha/beta signaling
RNF14 ring finger protein 14
  • Antigen processing: Ubiquitination & Proteasome degradation
RNF4 ring finger protein 4
  • Processing of DNA double-strand break ends
  • Antigen processing: Ubiquitination & Proteasome degradation
RNF6 ring finger protein 6
  • Antigen processing: Ubiquitination & Proteasome degradation
RUNX1 RUNX family transcription factor 1
  • Pre-NOTCH Transcription and Translation
  • Organic cation transport
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
  • RUNX1 regulates estrogen receptor mediated transcription
  • Regulation of RUNX1 Expression and Activity
  • Regulation of RUNX1 Expression and Activity
  • RUNX1 regulates expression of components of tight junctions
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • RUNX1 regulates transcription of genes involved in BCR signaling
  • RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
  • RUNX1 regulates transcription of genes involved in interleukin signaling
  • RUNX1 regulates transcription of genes involved in WNT signaling
  • RUNX2 regulates genes involved in differentiation of myeloid cells
  • RUNX3 regulates p14-ARF
  • Estrogen-dependent gene expression
  • Transcriptional regulation of granulopoiesis
  • Chronic myeloid leukemia (CML)
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
  • Acute myeloid leukemia (AML)
  • Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)

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