Search Results for: AR

265 interactions involving AR - androgen receptor found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
TCF4 transcription factor 4
  • Myogenesis
  • Myogenesis
  • Pitt-Hopkins syndrome, including: Pitt-Hopkins syndrome; Pitt-Hopkins-like syndrome
TGIF1 TGFB induced factor homeobox 1
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Holoprosencephaly (HPE)
USP10 ubiquitin specific peptidase 10
  • Termination of translesion DNA synthesis
  • Ub-specific processing proteases
WIPI1 WD repeat domain, phosphoinositide interacting 1
  • Macroautophagy
  • XBP1(S) activates chaperone genes
ZBTB16 zinc finger and BTB domain containing 16
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Skeletal defects, genital hypoplasia, and mental retardation
  • Acute myeloid leukemia (AML)
BAG1 BAG cochaperone 1
  • Regulation of HSF1-mediated heat shock response
  • (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CCAR2 cell cycle and apoptosis regulator 2
  • Regulation of HSF1-mediated heat shock response
CHD8 chromodomain helicase DNA binding protein 8
  • Deactivation of the beta-catenin transactivating complex
CTDSP2 CTD small phosphatase 2
  • XBP1(S) activates chaperone genes
DCAF6 DDB1 and CUL4 associated factor 6
  • Neddylation
DENND5A DENN domain containing 5A
  • RAB GEFs exchange GTP for GDP on RABs
ELF3 E74 like ETS transcription factor 3
  • Pre-NOTCH Transcription and Translation
FHL2 four and a half LIM domains 2
  • PPARA activates gene expression
FOXA1 forkhead box A1
  • Estrogen-dependent gene expression
GRIP1 glutamate receptor interacting protein 1
  • Trafficking of GluR2-containing AMPA receptors
HMGB2 high mobility group box 2
  • Apoptosis induced DNA fragmentation
JMJD1C jumonji domain containing 1C
  • Factors involved in megakaryocyte development and platelet production
KAT7 lysine acetyltransferase 7
  • HATs acetylate histones
MATK megakaryocyte-associated tyrosine kinase
  • Downregulation of ERBB2 signaling
  • Fostamatinib
MLH3 mutL homolog 3
  • Meiotic recombination
  • Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome

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