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PPAT |
phosphoribosyl pyrophosphate amidotransferase |
- Purine ribonucleoside monophosphate biosynthesis
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- L-Glutamine
- Mercaptopurine
- Dasatinib
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PPP6R2 |
protein phosphatase 6 regulatory subunit 2 |
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PQBP1 |
polyglutamine binding protein 1 |
- mRNA Splicing - Major Pathway
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- Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
- Non-syndromic X-linked mental retardation
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PRDM1 |
PR/SET domain 1 |
- Regulation of TP53 Expression
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PRR20A |
proline rich 20A |
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PRR20B |
proline rich 20B |
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PRR20C |
proline rich 20C |
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PRR20D |
proline rich 20D |
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PRR20E |
proline rich 20E |
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PRRC2A |
proline rich coiled-coil 2A |
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PRRC2B |
proline rich coiled-coil 2B |
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PSMC3 |
proteasome 26S subunit, ATPase 3 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- Neutrophil degranulation
- CDT1 association with the CDC6:ORC:origin complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- Antigen processing: Ubiquitination & Proteasome degradation
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PSPH |
phosphoserine phosphatase |
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- Zinc
- 3-Phosphono-D-alanine
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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PTGDS |
prostaglandin D2 synthase |
- Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
- Transcriptional regulation of testis differentiation
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PUM1 |
pumilio RNA binding family member 1 |
- Golgi Associated Vesicle Biogenesis
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QKI |
QKI, KH domain containing RNA binding |
- Signaling by BRAF and RAF fusions
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QRICH1 |
glutamine rich 1 |
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R3HDM1 |
R3H domain containing 1 |
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R3HDM2 |
R3H domain containing 2 |
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RAD54L2 |
RAD54 like 2 |
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