SLC23A1 and AHCYL1

Data Source:
BioGRID (two hybrid)

		SLC23A1	AHCYL1
Description		solute carrier family 23 member 1	adenosylhomocysteinase like 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Apical Plasma Membrane Intracellular Organelle Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	Transporter Activity Protein Binding L-ascorbate:sodium Symporter Activity Sodium Ion Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding
	Biological Process	Sodium Ion Transport Brain Development Response To Toxic Substance Nucleobase Transport L-ascorbic Acid Transmembrane Transport L-ascorbic Acid Metabolic Process Lung Development Sodium Ion Transmembrane Transport Dehydroascorbic Acid Transport Transepithelial L-ascorbic Acid Transport	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Apoptotic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Regulation Of Cardiac Conduction Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways		Vitamin C (ascorbate) metabolism	PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Malaria ( 31844061)	Height ( 31562340)
Interacting Genes		24 interacting genes: ADAMTSL4 AHCYL1 CYSRT1 EFEMP2 HOXA1 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-2 KRTAP9-3 MEOX2 MTUS2 NBPF19 NOTCH2NLA	25 interacting genes: BID CDKN2C DACH1 GEM HBQ1 HEXIM2 HGS HSPA6 ITPR1 JOSD2 LRRK2 MEOX2 MFHAS1 PLEKHG5 PPL PRDM6 PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 SUMO2 UACA ZNF165
Entrez ID		9963	10768
HPRD ID		04810	07613
Ensembl ID		ENSG00000170482	ENSG00000168710
Uniprot IDs		Q9UHI7	A0A024R0A8 O43865
PDB IDs			3MTG
Enriched GO Terms of Interacting Partners?
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