TBC1D4 and RBM12

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TBC1D4	RBM12
Description		TBC1 domain family member 4	RNA binding motif protein 12
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GO Annotations	Cellular Component	Cytosol Vesicle	Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	GTPase Activator Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Negative Regulation Of Vesicle Fusion Cellular Response To Insulin Stimulus Activation Of GTPase Activity	Regulation Of RNA Splicing
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Diabetic retinopathy ( 23562823) Eosinophil counts ( 32888494) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heart failure ( 20445134) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 27863252) Mean reticulocyte volume ( 32888494) Red blood cell count ( 29403010 32888494 27863252) Two-hour glucose ( 25043022) Type 2 diabetes ( 29926116) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Blood protein levels ( 28240269) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: AKT1 CDK5RAP2 EP400 FBXW11 LAMTOR5 NAV1 NFAT5 PIN1 RBM12 RESF1 TASOR TET2 TOPBP1 U2SURP YWHAG ZMIZ1	5 interacting genes: BRAP GIGYF2 OPTN PRMT2 TBC1D4
Entrez ID		9882	10137
HPRD ID		18164	06212
Ensembl ID		ENSG00000136111	ENSG00000244462
Uniprot IDs		A0A3B3IRT3 O60343	Q9NTZ6
PDB IDs		3QYB	1WEL 2CPY 2DNN 2EK1 2EK6
Enriched GO Terms of Interacting Partners?
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