GIT2 and ATF5

Data Source:
BioGRID (two hybrid)

		GIT2	ATF5
Description		GIT ArfGAP 2	activating transcription factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Centrosome Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Tubulin Binding Kinase Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Negative Regulation Of Cell Population Proliferation Post-embryonic Development Olfactory Bulb Interneuron Development Cerebellar Granule Cell Precursor Proliferation Multicellular Organism Growth Negative Regulation Of Apoptotic Process Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centrosome Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition
Pathways			Response of EIF2AK1 (HRI) to heme deficiency
Drugs			Pseudoephedrine
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	17 interacting genes: ATXN1 CCDC6 CCND3 CDC34 CEBPA CEBPE CEBPG DISC1 EIF2B1 EP300 FBXO7 GABBR1 GABBR2 GIT2 GPS2 SYCE1L TTR
Entrez ID		9815	22809
HPRD ID		09779	05906
Ensembl ID		ENSG00000139436	ENSG00000169136
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	A0A024QZG3 Q9Y2D1
PDB IDs
Enriched GO Terms of Interacting Partners?
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