CKAP5 and SLAIN2

Data Source:
BioGRID (two hybrid, two hybrid)

		CKAP5	SLAIN2
Description		cytoskeleton associated protein 5	SLAIN motif family member 2
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GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Gamma-tubulin Complex Nucleolus Cytoplasm Centrosome Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Protein-containing Complex Microtubule Plus-end	Centrosome Cytosol Microtubule Cytoskeleton Microtubule Plus-end
	Molecular Function	Protein Binding Microtubule Binding Ribonucleoprotein Complex Binding Cadherin Binding Microtubule Plus End Polymerase	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Depolymerization Spindle Organization Mitotic Spindle Organization Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Microtubule Polymerization RNA Transport Centrosome Duplication Cell Division Positive Regulation Of Microtubule Nucleation Ciliary Basal Body-plasma Membrane Docking	Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase AURKA Activation by TPX2 EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Immunoglobulin A ( 20694011) Pulse pressure ( 30578418) Schizophrenia ( 29483656)	Bipolar disorder ( 31043756) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Uterine fibroids ( 30194396)
Interacting Genes		11 interacting genes: ARHGEF16 AURKA CACNA1A CLASP1 CLK1 NDC80 PTPRN2 SLAIN2 SUMO2 TOP1 USP19	11 interacting genes: APP CASK CKAP5 DAPK1 MAPRE2 PTPRD SGO2 SMURF1 SRPK1 SRPK2 TULP3
Entrez ID		9793	57606
HPRD ID		10830	13863
Ensembl ID		ENSG00000175216	ENSG00000109171
Uniprot IDs		Q14008	A0A024R9T6 Q9P270
PDB IDs		4QMI 4QMJ	3RDV
Enriched GO Terms of Interacting Partners?
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