SERTAD2 and HELLS

Data Source:
BioGRID (two hybrid)

		SERTAD2	HELLS
Description		SERTA domain containing 2	helicase, lymphoid specific
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Chromosome, Centromeric Region Nucleus Pericentric Heterochromatin
	Molecular Function	Transcription Coactivator Activity Protein Binding Transcription Regulator Activity	Chromatin Binding Helicase Activity Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Cell Growth Chromatin-mediated Maintenance Of Transcription	DNA Methylation DNA Methylation-dependent Heterochromatin Assembly Cell Cycle Multicellular Organism Development Maintenance Of DNA Methylation Pericentric Heterochromatin Assembly Lymphocyte Proliferation Cell Division
Pathways
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Apolipoprotein B levels ( 32203549) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Visceral fat ( 22589738)	Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Red cell distribution width ( 32888494) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes		25 interacting genes: ATG12 C1orf109 CDC7 CKS1B CREBBP CTNNA3 E2F1 ESPNL HELLS IGFN1 KAT2B KAT5 PARVG PIK3R3 PLA2G6 PRKAB2 STRA8 SUPT7L TFDP1 TNS2 TRIM28 XPO1 ZNF524 ZNF581 ZSCAN22	9 interacting genes: - APP DNMT1 DNMT3B E2F3 GTSF1L HDAC1 MEOX2 SERTAD2
Entrez ID		9792	3070
HPRD ID		18040	07232
Ensembl ID		ENSG00000179833	ENSG00000119969
Uniprot IDs		Q14140	A0A087WSW7 A0A0B4J1V9 F6XU50 Q0VGL2 Q76H82 Q9NRZ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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