SERTAD2 and CEP68

Data Source:
BioGRID (proximity labelling technology)

		SERTAD2	CEP68
Description		SERTA domain containing 2	centrosomal protein 68
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Centrosome Cytosol Cell Junction Centriolar Satellite
	Molecular Function	Transcription Coactivator Activity Protein Binding Transcription Regulator Activity	Protein Binding Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Negative Regulation Of Cell Growth Chromatin-mediated Maintenance Of Transcription	Centrosome Cycle Centriole-centriole Cohesion Protein Localization To Organelle
Pathways
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Apolipoprotein B levels ( 32203549) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Visceral fat ( 22589738)	Apolipoprotein A1 levels ( 32203549) Atrial fibrillation ( 28416818 28416822 30061737 29892015) HDL cholesterol levels ( 32203549) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolic syndrome ( 31589552) Platelet distribution width ( 32888494) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418) Triglyceride levels ( 32203549) Triglycerides ( 30275531 25961943) Type 2 diabetes ( 30054458 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		25 interacting genes: ATG12 C1orf109 CDC7 CKS1B CREBBP CTNNA3 E2F1 ESPNL HELLS IGFN1 KAT2B KAT5 PARVG PIK3R3 PLA2G6 PRKAB2 STRA8 SUPT7L TFDP1 TNS2 TRIM28 XPO1 ZNF524 ZNF581 ZSCAN22	9 interacting genes: COG2 CTBP1 CTBP2 HGS MCM7 TRAF3IP3 TRIM54 TSNAX USHBP1
Entrez ID		9792	23177
HPRD ID		18040	13808
Ensembl ID		ENSG00000179833	ENSG00000011523
Uniprot IDs		Q14140	Q76N32
PDB IDs
Enriched GO Terms of Interacting Partners?
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