NUP93 and OPCML

Data Source:
BioGRID (two hybrid)

		NUP93	OPCML
Description		nucleoporin 93	opioid binding protein/cell adhesion molecule like
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GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Nuclear Periphery Host Cell	Extracellular Region Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	Protein Binding
	Biological Process	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Nuclear Envelope Organization Viral Process Protein Sumoylation Poly(A)+ MRNA Export From Nucleus Viral Transcription Nuclear Pore Complex Assembly Positive Regulation Of SMAD Protein Signal Transduction SMAD Protein Signal Transduction Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Cell Adhesion Neuron Recognition
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Gambling ( 22780124) HDL cholesterol ( 20031564) HDL cholesterol levels ( 32203549 26763881) Potassium levels ( 29403010)	Adult body size ( 32376654) Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Alcohol dependence ( 23942779) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Coffee consumption ( 31046077) Diverticular disease ( 30177863) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Gastric cancer ( 26129866) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota relative abundance (Sutterella) ( 33208821) Hallux valgus ( 32131869) Hand grip strength ( 29691431) Heart rate variability traits (SDNN) ( 28610988) Middle childhood and early adolescence aggressive behavior ( 26087016) Refractive error ( 32231278) Sleep-related phenotypes ( 17903308) Smoking status (ever vs never smokers) ( 30643258) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Takayasu arteritis ( 25604533) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-hip ratio ( 23966867)
Interacting Genes		7 interacting genes: AP5Z1 MPPED2 NDC1 NUP205 OPCML PLA2G6 TMEM100	7 interacting genes: ATXN1 KRT40 KRTAP10-3 KRTAP10-8 KRTAP5-2 NUP93 PRNP
Entrez ID		9688	4978
HPRD ID		14854	07198
Ensembl ID		ENSG00000102900	ENSG00000183715
Uniprot IDs		Q8N1F7	A8K0Y0 B2CZX3 B7ZLQ0 Q14982
PDB IDs		5IJN 5IJO	5UV6
Enriched GO Terms of Interacting Partners?
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