OPCML and NUP93

Data Source:
BioGRID (two hybrid)

		OPCML	NUP93
Description		opioid binding protein/cell adhesion molecule like	nucleoporin 93
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane	Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Nuclear Periphery Host Cell
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Cell Adhesion Neuron Recognition	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Nuclear Envelope Organization Viral Process Protein Sumoylation Poly(A)+ MRNA Export From Nucleus Viral Transcription Nuclear Pore Complex Assembly Positive Regulation Of SMAD Protein Signal Transduction SMAD Protein Signal Transduction Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Alcohol dependence ( 23942779) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Coffee consumption ( 31046077) Diverticular disease ( 30177863) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Gastric cancer ( 26129866) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota relative abundance (Sutterella) ( 33208821) Hallux valgus ( 32131869) Hand grip strength ( 29691431) Heart rate variability traits (SDNN) ( 28610988) Middle childhood and early adolescence aggressive behavior ( 26087016) Refractive error ( 32231278) Sleep-related phenotypes ( 17903308) Smoking status (ever vs never smokers) ( 30643258) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Takayasu arteritis ( 25604533) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-hip ratio ( 23966867)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Gambling ( 22780124) HDL cholesterol ( 20031564) HDL cholesterol levels ( 32203549 26763881) Potassium levels ( 29403010)
Interacting Genes		7 interacting genes: ATXN1 KRT40 KRTAP10-3 KRTAP10-8 KRTAP5-2 NUP93 PRNP	7 interacting genes: AP5Z1 MPPED2 NDC1 NUP205 OPCML PLA2G6 TMEM100
Entrez ID		4978	9688
HPRD ID		07198	14854
Ensembl ID		ENSG00000183715	ENSG00000102900
Uniprot IDs		A8K0Y0 B2CZX3 B7ZLQ0 Q14982	Q8N1F7
PDB IDs		5UV6	5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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