CD53 and MS4A3

Data Source:
BioGRID (two hybrid)

		CD53	MS4A3
Description		CD53 molecule	membrane spanning 4-domains A3
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Signal Transduction Neutrophil Degranulation Positive Regulation Of Myoblast Fusion	Neutrophil Degranulation Regulation Of Cell Cycle
Pathways		Neutrophil degranulation	Neutrophil degranulation
Drugs
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)	Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)
Interacting Genes		80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1	38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1
Entrez ID		963	932
HPRD ID		01054	09403
Ensembl ID		ENSG00000143119	ENSG00000149516
Uniprot IDs		B4DQB5 P19397	Q96HJ5
PDB IDs		6WVG
Enriched GO Terms of Interacting Partners?
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