AATK and MTMR8

Data Source:
BioGRID (two hybrid)

		AATK	MTMR8
Description		apoptosis associated tyrosine kinase	myotubularin related protein 8
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Phosphatidylinositol-3-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity
	Biological Process	Protein Phosphorylation Brain Development Biological_process Peptidyl-tyrosine Autophosphorylation	Phosphatidylinositol Biosynthetic Process Negative Regulation Of Autophagy Regulation Of Macroautophagy Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Beef consumption ( 32066663) Lymphocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		43 interacting genes: BDKRB2 CDC14A CDC25B CDK5 DUSP1 DUSP14 DUSP29 DUSP5 DUSP6 DUSP9 ERBB2 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TEPSIN TPTE2	3 interacting genes: AATK ERBB3 MTMR9
Entrez ID		9625	55613
HPRD ID		05591	06664
Ensembl ID		ENSG00000181409	ENSG00000102043
Uniprot IDs		H7C175 Q6ZMQ8	Q96EF0
PDB IDs			4Y7I
Enriched GO Terms of Interacting Partners?
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