RBM39 and CLK2

Data Source:
BioGRID (two hybrid)

		RBM39	CLK2
Description		RNA binding motif protein 39	CDC like kinase 2
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GO Annotations	Cellular Component	Nucleoplasm Microtubule Cytoskeleton Nuclear Speck Protein-containing Complex Centriolar Satellite	Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	RNA Binding Protein Binding RS Domain Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	RNA Processing MRNA Processing RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Blood protein levels ( 28240269) Refractive error ( 32231278)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		60 interacting genes: AK8 APP ARL6IP4 BANP CDC42 CHERP CLK1 CLK2 CSNK2A1 CSNK2B DARS1-AS1 DDX39B DVL3 ESR1 ESR2 FAM200A GOLGA2 H1-2 HNRNPH2 HOMEZ HSPB1 INO80B JUN KHDC4 KRTAP12-2 MCPH1 MLX MTNR1A NCOA6 NKAP NKAPD1 PGR PHC2 POU6F2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1 SREK1IP1 SRPK1 SRPK2 SRRM4 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10	53 interacting genes: AKT1 ASPSCR1 CACTIN CLASRP CLK1 CLK3 CPSF7 DDIT4L ECE1 EHHADH GMCL1 GTPBP2 KLHL2 LNX1 LUZP4 MRPL4 NXF1 PRM1 PRPF38A PTPN1 RBM39 RNF8 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 SRSF3 TACC2 TRIM27 TRIM50 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF136 ZNF263 ZNF317 ZNF394 ZNF398 ZNF436 ZNF440 ZNF473 ZNF491 ZNF558 ZNF764 ZNF768 ZNF837 ZRSR2 ZSCAN21
Entrez ID		9584	1196
HPRD ID		09201	04289
Ensembl ID		ENSG00000131051	ENSG00000176444
Uniprot IDs		A0A384NQ03 B4DRA0 E1P5S2 Q14498 Q6N037	A8K7I0 B7Z8N6 P49760
PDB IDs		2JRS 2MHN 4OO6 4OZ0 4OZ1 4YUD 6PAI 6Q0R 6Q0V 6Q0W 6SJ7 6UD7 6UE5	3NR9 5UNP 6FYI 6FYK 6FYL 6KHE
Enriched GO Terms of Interacting Partners?
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