ENTPD3 and PTPN5

Data Source:
BioGRID (two hybrid)

		ENTPD3	PTPN5
Description		ectonucleoside triphosphate diphosphohydrolase 3	protein tyrosine phosphatase non-receptor type 5
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Guanosine-diphosphatase Activity Protein Binding ATP Binding Nucleoside-diphosphatase Activity Nucleoside-triphosphatase Activity Uridine-diphosphatase Activity DATP Phosphohydrolase Activity DCTP Phosphohydrolase Activity DUTP Phosphohydrolase Activity DTTP Phosphohydrolase Activity GTP Phosphohydrolase Activity 8-oxo-dGTP Phosphohydrolase Activity DGTP Phosphohydrolase Activity	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Nucleoside Diphosphate Catabolic Process Nucleoside Triphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus
Pathways		Phosphate bond hydrolysis by NTPDase proteins	Interleukin-37 signaling
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Neuroticism ( 29255261)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: ARL13B CREB3L1 ERGIC3 FAM209A FNDC9 GGT6 GPA33 IFNGR2 LEUTX LHFPL5 LMNA MUC1 PTPN5 STX2 SYNE4 TMEM106A	19 interacting genes: CCNQ CLEC4G CUL5 CXCL9 CYB561D2 ENTPD3 FYN MAPK1 MAPK3 MARCHF5 MOB1A PRKN SLC35B1 SNX4 TERF1 TMEM201 TMEM51 VTI1B ZBTB5
Entrez ID		956	84867
HPRD ID		16014	01472
Ensembl ID		ENSG00000168032	ENSG00000110786
Uniprot IDs		O75355	B7Z2F8 P54829 Q86TL3
PDB IDs			2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
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