ENTPD3 and TMEM106A

Data Source:
BioGRID (two hybrid)

		ENTPD3	TMEM106A
Description		ectonucleoside triphosphate diphosphohydrolase 3	transmembrane protein 106A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Guanosine-diphosphatase Activity Protein Binding ATP Binding Nucleoside-diphosphatase Activity Nucleoside-triphosphatase Activity Uridine-diphosphatase Activity DATP Phosphohydrolase Activity DCTP Phosphohydrolase Activity DUTP Phosphohydrolase Activity DTTP Phosphohydrolase Activity GTP Phosphohydrolase Activity 8-oxo-dGTP Phosphohydrolase Activity DGTP Phosphohydrolase Activity	Molecular_function Protein Binding
	Biological Process	Nucleoside Diphosphate Catabolic Process Nucleoside Triphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process	Biological_process Interleukin-1 Beta Production Interleukin-6 Production Tumor Necrosis Factor Production CD80 Biosynthetic Process CD86 Biosynthetic Process Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process
Pathways		Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Neuroticism ( 29255261)	Blood protein levels ( 30072576)
Interacting Genes		16 interacting genes: ARL13B CREB3L1 ERGIC3 FAM209A FNDC9 GGT6 GPA33 IFNGR2 LEUTX LHFPL5 LMNA MUC1 PTPN5 STX2 SYNE4 TMEM106A	13 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM106C TMEM107 TMEM128 TMEM86B TNMD TSPAN4
Entrez ID		956	113277
HPRD ID		16014	11315
Ensembl ID		ENSG00000168032	ENSG00000184988
Uniprot IDs		O75355	B7Z779 Q96A25
PDB IDs
Enriched GO Terms of Interacting Partners?
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