SEC22B and FAM174A

Data Source:
BioGRID (two hybrid)

		SEC22B	FAM174A
Description		SEC22 homolog B, vesicle trafficking protein	family with sequence similarity 174 member A
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Phagocytic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome	Integral Component Of Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus Negative Regulation Of Autophagosome Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Pathways		ER-Phagosome pathway COPII-mediated vesicle transport Cargo concentration in the ER COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Iris color (L* coordinate) ( 30895295)	Heel bone mineral density ( 30598549)
Interacting Genes		56 interacting genes: ABHD16A AIG1 AQP6 B3GAT3 CD79A CERS6 CLDN7 CLRN1 CPLX4 CREB3 CREB3L1 DPM3 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCER1G FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPX8 HIBADH HSD17B11 HSD17B13 IFNGR2 JAGN1 KIR2DL3 LHFPL1 LHFPL5 LMNA MFF MFSD5 MGST2 MGST3 MMGT1 MRPS18B NDUFAF2 REEP4 RELL2 RHBDD1 SERINC2 SLC35C2 STX1A STX2 STX4 STX5 TLCD4 TM4SF19 TMEM139 TMEM167B TMEM229B TMEM86B	36 interacting genes: ANKRD46 BET1 BNIP1 C14orf180 C4orf3 CCDC167 CMTM7 DEFB127 ERG28 FKBP8 GIMAP1 GIMAP5 GOSR2 HMOX1 LCK PLLP PLPP6 RTP2 SEC22A SEC22B SERP1 SLC30A2 SMCO4 SMIM1 STX7 STX8 TMEM11 TMEM203 TMEM222 TMEM239 TMEM243 TMEM42 TMEM65 TREX1 VAMP3 VAPB
Entrez ID		9554	345757
HPRD ID		04939	18260
Ensembl ID		ENSG00000265808	ENSG00000174132
Uniprot IDs		O75396	Q8TBP5
PDB IDs		2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?
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