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TECR and STING1
Data Source:
BioGRID
(two hybrid)
TECR
STING1
Description
trans-2,3-enoyl-CoA reductase
stimulator of interferon response cGAMP interactor 1
Image
GO Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Autophagosome Membrane
Nucleoplasm
Mitochondrial Outer Membrane
Endosome
Autophagosome
Peroxisome
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Plasma Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Cytoplasmic Vesicle Membrane
Secretory Granule Membrane
Perinuclear Region Of Cytoplasm
Integral Component Of Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Molecular Function
Protein Binding
Oxidoreductase Activity
Very-long-chain Enoyl-CoA Reductase Activity
Protein Binding
Transcription Factor Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Cyclic-di-GMP Binding
Identical Protein Binding
Protein Homodimerization Activity
Cyclic-GMP-AMP Binding
Biological Process
Sphingolipid Metabolic Process
Fatty Acid Elongation
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Autophagosome Assembly
Activation Of Innate Immune Response
Positive Regulation Of Defense Response To Virus By Host
Viral Process
Positive Regulation Of Macroautophagy
Positive Regulation Of Protein Binding
Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Interferon-beta Production
Cellular Response To Interferon-beta
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Inflammatory Response
Positive Regulation Of DNA-binding Transcription Factor Activity
Protein Complex Oligomerization
Defense Response To Virus
Reticulophagy
Cellular Response To Exogenous DsRNA
Cellular Response To Organic Cyclic Compound
Pathways
Synthesis of very long-chain fatty acyl-CoAs
STING mediated induction of host immune responses
Regulation of innate immune responses to cytosolic DNA
STAT6-mediated induction of chemokines
IRF3-mediated induction of type I IFN
Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes
28 interacting genes:
ARL13B
CD79A
CLDN5
CRB3
CREB3
CREB3L1
ELOVL4
ERGIC3
FAM209A
FBXO7
GET1
GOLT1A
HACD1
JAGN1
MFSD14B
MMGT1
MUC1
NOS3
PAXIP1
PGRMC2
PTEN
RETREG3
SLC10A6
SLC7A14
STING1
STOM
TFAM
VMA21
22 interacting genes:
CCDC47
CMTM5
DDOST
IRAK1
LEPROTL1
LTN1
MBOAT7
MUL1
PLLP
REEP6
RNF26
SGPL1
SMIM1
STT3A
STX5
SURF4
TECR
TMEM100
TRIM32
USP20
USP49
YIPF2
Entrez ID
9524
340061
HPRD ID
17076
14173
Ensembl ID
ENSG00000099797
ENSG00000184584
Uniprot IDs
B3KSQ1
Q9NZ01
J3QTB1
Q86WV6
V5V0K2
PDB IDs
2DZJ
4EF4
4EF5
4EMT
4EMU
4F5D
4F5E
4F5W
4F5Y
4F9E
4F9G
4KSY
4LOH
4LOI
4QXO
4QXP
4QXQ
4QXR
5BQX
5JEJ
6CFF
6CY7
6DNK
6DXG
6DXL
6MX0
6MX3
6MXE
6NT5
6O8B
6O8C
6RM0
6S26
6S27
6S86
6UKM
6UKU
6UKV
6UKW
6UKX
6UKY
6UKZ
6UL0
6XNP
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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