ACY1 and PRR35

		ACY1	PRR35
Description		aminoacylase 1	proline rich 35
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome
	Molecular Function	Aminoacylase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process
Pathways		Aflatoxin activation and detoxification Defective ACY1 causes encephalopathy
Drugs		Aspartic acid Acetylcysteine Copper
Diseases
GWAS
Interacting Genes		12 interacting genes: APP BCAS2 NPM1 NTAQ1 NUDT1 POT1 PRR35 TENT5B TERF1 TLX3 TTC1 WWOX	80 interacting genes: ABHD11 ACY1 APPL2 ARMC5 ASB15 BEGAIN BIRC7 BPIFA1 C11orf1 C19orf54 CARD10 CCDC136 CNOT2 CRX CYSRT1 EXOC8 FAM168B FHL3 FRYL GIGYF1 GRAP2 HOMER3 HOOK2 HPCA HSPB2 HSPB2-C11orf52 INSC INTS11 JUP KLHL26 KRT31 KRT34 KRT35 KRTAP10-7 KRTAP12-1 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LONRF1 LZTS2 MAGED1 MCCD1 MKRN3 MSS51 MTUS2 N4BP3 NBPF19 NOTCH2NLA OIP5 OXER1 PFDN5 PLAGL2 PPIL1 PPP1R13B PRR20A PRR20B PRR20C PRR20D PRR20E PSTPIP1 RBPMS RNF144B RUSC1 SMUG1 SPAG8 TBX19 TLE5 TRIM27 TRIM54 TRIM73 TTC19 TTLL12 UBASH3B UBXN11 USP54 ZMYND12 ZNF655
Entrez ID		95	146325
HPRD ID		00092	10046
Ensembl ID		ENSG00000243989	ENSG00000161992
Uniprot IDs		Q03154 V9HWA0	P0CG20
PDB IDs		1Q7L
Enriched GO Terms of Interacting Partners?
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