HOMER1 and TANC1

Data Source:
HPRD (in vitro, in vivo)

		HOMER1	TANC1
Description		homer scaffold protein 1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Z Disc Axon Dendrite Costamere Dendritic Spine Neuron Spine Apical Part Of Cell Glutamatergic Synapse Postsynaptic Cytosol	Postsynaptic Density Dendrite Neuronal Cell Body Axon Terminus
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Signaling Adaptor Activity Ion Channel Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Signal Transduction Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Protein Tetramerization Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Calcium Ion Import Regulation Of Postsynaptic Neurotransmitter Receptor Activity Regulation Of Dendritic Spine Maintenance Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Myoblast Fusion Visual Learning Dendritic Spine Maintenance
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood and toenail selenium levels ( 25343990) Height ( 18193045) Hepcidin/ferritin ratio ( 27846281) Lateral ventricle temporal horn volume ( 31530798) Major depressive disorder ( 20673876) Metabolite levels ( 23823483) Toenail selenium levels ( 25343990)	Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Nicotine dependence ( 28440896) Night sleep phenotypes ( 27126917) Response to radiotherapy in prostate cancer (toxicity) ( 24974847) Resting heart rate ( 27798624) Restless legs syndrome ( 29029846) Tourette syndrome ( 30818990)
Interacting Genes		34 interacting genes: ABI1 ABI3 AGAP2 AIMP1 BRME1 C1orf116 CENPQ DBNL DNM3 EFNB2 FAM9A FAT1 FCHSD2 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 NUP54 PATJ PIAS2 RAD54L2 RASAL3 RYR1 RYR2 SHANK1 SHANK2 STX12 SYCE2 TANC1 TRAF5 TRPC1 ZMYM5	12 interacting genes: ACTB CAMK2A CASK DLG1 DLG4 DLGAP1 GRIA1 GRIN2B HOMER1 INA SHANK1 SPTAN1
Entrez ID		9456	85461
HPRD ID		09211	18146
Ensembl ID		ENSG00000152413	ENSG00000115183
Uniprot IDs		Q5U5K4 Q86YM7	B9EK39 Q9C0D5
PDB IDs
Enriched GO Terms of Interacting Partners?
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