MED17 and MED22

Data Source:
HPRD (in vitro)

		MED17	MED22
Description		mediator complex subunit 17	mediator complex subunit 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Membrane Mediator Complex Core Mediator Complex	Cytoplasm Mediator Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter	Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Malaria ( 31844061)
Interacting Genes		16 interacting genes: BCL6 CTDP1 ESR1 ESR2 HEMGN HNF4A MED19 MED22 MED30 MED8 PPARGC1A SMARCA4 SREBF1 SUZ12 TP53 USP49	12 interacting genes: FBXO7 GOLM1 HGS MED11 MED17 MED27 MED30 MED8 MED9 NTAQ1 THOC7 TXNDC9
Entrez ID		9440	6837
HPRD ID		04816	01713
Ensembl ID		ENSG00000042429	ENSG00000148297
Uniprot IDs		Q9NVC6	A0A024R8C5 Q15528
PDB IDs
Enriched GO Terms of Interacting Partners?
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