PPP1R14A and CSNK1G3

Data Source:
HPRD (in vitro)

		PPP1R14A	CSNK1G3
Description		protein phosphatase 1 regulatory inhibitor subunit 14A	casein kinase 1 gamma 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Inhibitor Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphorylation	Cellular Protein Modification Process Endocytosis Signal Transduction Wnt Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		RHO GTPases activate PKNs
Drugs			Purvalanol A {4-Amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-methoxyphenyl)methanone 4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium K-00546
Diseases
GWAS		Diverticular disease ( 30177863)	Adult asthma ( 27611488) Amyotrophic lateral sclerosis ( 19451621) Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068) Chronotype ( 30696823) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Diastolic blood pressure ( 27618452 30578418) Heel bone mineral density ( 30598549 28869591) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 23823483) Nickel levels ( 26025379) Pulse pressure ( 27618448) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618452) Total body bone mineral density ( 29304378) Total cholesterol levels ( 28334899) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ	5 interacting genes: DBNDD2 DRICH1 KRTAP10-10 MDFI PPP1R14A
Entrez ID		94274	1456
HPRD ID		16291	05034
Ensembl ID		ENSG00000167641	ENSG00000151292
Uniprot IDs		Q96A00	Q9Y6M4
PDB IDs			2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS 6GRO
Enriched GO Terms of Interacting Partners?
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