FAM189A2 and OPTN

  • Data Source:
  • BioGRID (two hybrid)

FAM189A2

OPTN

Description family with sequence similarity 189 member A2 optineurin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes 10 interacting genes: BAG3 CALCOCO2 OPTN SFN STAM2 TAX1BP1 UBQLN1 UBXN1 WWP1 WWP2 69 interacting genes: AIMP1 ARRDC3 ATG16L1 ATG5 CALM1 CCDC13 CDC23 CLTC CMYA5 DAZAP2 DYSF DZIP1 FAM189A2 FLII FOS FTH1 GABARAP GABARAPL1 GABARAPL2 GNAS GRM1 GTF3A HACE1 HSF2BP HSPB1 HTT IRAK1 KANSL1L LITAF LNX2 MAP1LC3A MAP1LC3C MPP1 MYH3 MYO6 PIAS4 PICK1 POU6F2 RAB11A RAB11B RAB12 RAB14 RAB25 RAB8A RBM12 RFFL RNF11 RNF216 SDCBP SLF2 SNX6 TBC1D15 TBC1D17 TNIP1 UBB UBC UQCRQ USP2 VCP WASHC3 WIPI2 ZNF17 ZNF181 ZNF302 ZNF329 ZNF398 ZNF426 ZNF670 ZNF711
Entrez ID 9413 10133
HPRD ID 16255 03891
Ensembl ID ENSG00000135063 ENSG00000123240
Uniprot IDs A0A0A0MR12 A0A6F8PH59 Q15884 Q8WU02 Q96CV9
PDB IDs 2LO4 2LUE 3VTV 3VTW 5AAZ 5B83 5EOA 5EOF
Enriched GO Terms of Interacting Partners?
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