MED21 and SSC5D

Data Source:
BioGRID (two hybrid, two hybrid)

		MED21	SSC5D
Description		mediator complex subunit 21	scavenger receptor cysteine rich family member with 5 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mediator Complex	Extracellular Space Cytoplasm Membrane Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II	Endocytosis Defense Response Multicellular Organism Development Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Scavenging by Class B Receptors
Drugs
Diseases
GWAS		Dimensional psychopathology (Social) ( 29496196)	Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		30 interacting genes: BLOC1S6 BORCS6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HGS HNF4A HTT MAGEA6 MAGEB4 MED29 MIEF1 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 TRIM72 VAV2 ZNF655 ZSCAN1	17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1
Entrez ID		9412	284297
HPRD ID		09156	11444
Ensembl ID		ENSG00000152944	ENSG00000179954
Uniprot IDs		A0A024RAW0 Q13503	A1L4H1
PDB IDs
Enriched GO Terms of Interacting Partners?
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