SSC5D and SKA1

Data Source:
BioGRID (two hybrid)

		SSC5D	SKA1
Description		scavenger receptor cysteine rich family member with 5 domains	spindle and kinetochore associated complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane Extracellular Matrix Collagen-containing Extracellular Matrix	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding	Protein Binding Microtubule Binding
	Biological Process	Endocytosis Defense Response Multicellular Organism Development Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Scavenging by Class B Receptors	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Height ( 28552196) Lung adenocarcinoma ( 28604730)	Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)
Interacting Genes		17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1	13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1
Entrez ID		284297	220134
HPRD ID		11444	12689
Ensembl ID		ENSG00000179954	ENSG00000154839
Uniprot IDs		A1L4H1	A0A024R294 Q96BD8
PDB IDs			4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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