CIAO1 and URI1

Data Source:
BioGRID (two hybrid)

		CIAO1	URI1
Description		cytosolic iron-sulfur assembly component 1	URI1 prefoldin like chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm MMXD Complex CIA Complex	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Dendrite
	Molecular Function	Protein Binding	RNA Polymerase II Complex Binding Chromatin Binding Transcription Corepressor Activity Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Inhibitor Activity Phosphoprotein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Population Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Regulation Of Transcription By RNA Polymerase II Response To Virus Negative Regulation Of Phosphatase Activity Negative Regulation Of Phosphoprotein Phosphatase Activity Cellular Response To Growth Factor Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS			Body mass index ( 26426971) Cerebrospinal P-tau181p levels ( 28247064) Diastolic blood pressure ( 27841878) Serum urate levels in chronic kidney disease ( 30181573)
Interacting Genes		18 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SF1 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B URI1 WT1	10 interacting genes: APP ATF7 CIAO1 DMAP1 GTF2F2 ITCH NEDD4 POLR2E RPS6KB1 STAP1
Entrez ID		9391	8725
HPRD ID		16057	11943
Ensembl ID		ENSG00000144021	ENSG00000105176
Uniprot IDs		O76071	O94763
PDB IDs		3FM0
Enriched GO Terms of Interacting Partners?
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