CIAO1 and PGRMC1

Data Source:
BioGRID (two hybrid)

		CIAO1	PGRMC1
Description		cytosolic iron-sulfur assembly component 1	progesterone receptor membrane component 1
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GO Annotations	Cellular Component	Cytoplasm MMXD Complex CIA Complex	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Population Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	Heme Biosynthetic Process Neutrophil Degranulation
Pathways		Cytosolic iron-sulfur cluster assembly	Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS
Interacting Genes		18 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SF1 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B URI1 WT1	20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71
Entrez ID		9391	10857
HPRD ID		16057	02338
Ensembl ID		ENSG00000144021	ENSG00000101856
Uniprot IDs		O76071	O00264 Q6IB11
PDB IDs		3FM0	4X8Y
Enriched GO Terms of Interacting Partners?
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