ZFYVE9 and ETS2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZFYVE9	ETS2
Description		zinc finger FYVE-type containing 9	ETS proto-oncogene 2, transcription factor
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GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways			Oncogene Induced Senescence
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 25673413) Body size at age 10 ( 32376654) C-reactive protein levels ( 30388399) Central corneal thickness ( 32528159) Eye morphology ( 29921221) Fibrinogen levels ( 28107422) Fractures ( 30158200) Intraocular pressure ( 29617998) Non-small cell lung cancer (survival) ( 21079520) Periodontitis (Mean PAL) ( 24024966) Schizophrenia ( 30285260) TPE interval (response to exercise) ( 32386560)
Interacting Genes		38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	20 interacting genes: CDK10 COP1 CREBBP EP300 ERG ETS1 FOS GATA3 JUN NCOR1 NR3C1 POU5F1 SMARCA4 SPI1 SRA1 SRC STAT5B TDP2 ZFYVE9 ZMYND11
Entrez ID		9372	2114
HPRD ID		04782	01263
Ensembl ID		ENSG00000157077	ENSG00000157557
Uniprot IDs		O95405	P15036
PDB IDs		1DEV 1MK2 4BKW 5MJY	4BQA 4MHV
Enriched GO Terms of Interacting Partners?
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