SYCE1 and CYTH3

Data Source:
BioGRID (two hybrid)

		SYCE1	CYTH3
Description		synaptonemal complex central element protein 1	cytohesin 3
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleoplasm Chromosome Cytosol Intracellular Membrane-bounded Organelle	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity
Pathways		Meiotic synapsis	Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS			Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
Interacting Genes		49 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 CYTH3 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HOOK1 HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 LMNA MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM1 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN
Entrez ID		93426	9265
HPRD ID		12598	05469
Ensembl ID		ENSG00000171772	ENSG00000008256
Uniprot IDs		A0A0B4J1R9 Q8N0S2	O43739
PDB IDs			4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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