CYTH3 and INAVA

Data Source:
BioGRID (pull down)

		CYTH3	INAVA
Description		cytohesin 3	innate immunity activator
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Nucleus Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Protein Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity	Activation Of MAPK Activity Pattern Recognition Receptor Signaling Pathway Cytokine Production Involved In Immune Response Positive Regulation Of Protein Ubiquitination Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Stress-activated MAPK Cascade Adherens Junction Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Intestinal Epithelial Structure Maintenance Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Reactive Oxygen Species Biosynthetic Process
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)	Celiac disease ( 30572963)
Interacting Genes		12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN	3 interacting genes: CYTH1 CYTH2 CYTH3
Entrez ID		9265	55765
HPRD ID		05469	07712
Ensembl ID		ENSG00000008256	ENSG00000163362
Uniprot IDs		O43739	Q3KP66
PDB IDs		4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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