MAGI1 and IGSF5

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MAGI1	IGSF5
Description		membrane associated guanylate kinase, WW and PDZ domain containing 1	immunoglobulin superfamily member 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Cell Junction Cell Projection Cell Periphery	Bicellular Tight Junction Cell Surface Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Alpha-actinin Binding Molecular Adaptor Activity
	Biological Process	Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Protein-containing Complex Assembly	Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 28334814) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cobalt levels ( 26025379) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Cortical surface area (MOSTest) ( 32665545) Crohn's disease-related phenotypes ( 25557950) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Knee osteoarthritis ( 28916551) Neurociticism ( 29500382) Neuroticism ( 25993607) Nicotine dependence symptom count ( 25555482) Ocular sarcoidosis ( 32141793) Ocular sarcoidosis in sarcoidosis ( 32141793) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 23534349) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Health literacy ( 31250787) Hypertension ( 21347282) Suicide risk ( 21041247) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Working memory ( 31598132)
Interacting Genes		25 interacting genes: ACTN4 ADGRB1 AMOT ASIC3 ATN1 CLCN5 CRHR1 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 RAC1 RASA1 RASL11B RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2	3 interacting genes: LNX1 LNX2 MAGI1
Entrez ID		9223	150084
HPRD ID		04020	19125
Ensembl ID		ENSG00000151276	ENSG00000183067
Uniprot IDs		Q96QZ7	Q9NSI5
PDB IDs		1WBP 2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU 5N7D 5N7F 5N7G 6TWU 6TWX 6TWY
Enriched GO Terms of Interacting Partners?
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