NOLC1 and KBTBD8

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		NOLC1	KBTBD8
Description		nucleolar and coiled-body phosphoprotein 1	kelch repeat and BTB domain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Cytoplasm Cajal Body Box C/D RNP Complex Box H/ACA SnoRNP Complex	Golgi Apparatus Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding ATP Binding GTP Binding Transcription Factor Binding Nuclear Localization Sequence Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Box C/D RNA Binding Box H/ACA SnoRNA Binding Protein Heterodimerization Activity Box C/D SnoRNP Complex Binding Box H/ACA SnoRNP Complex Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle RRNA Processing Regulation Of Translation Response To Osmotic Stress Nucleolus Organization Positive Regulation Of Cell Population Proliferation Neural Crest Formation Neural Crest Cell Development Box H/ACA RNA Metabolic Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription, DNA-templated	Regulation Of Translation Protein Monoubiquitination Neural Crest Formation Neural Crest Cell Development Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Doxorubicin
Diseases
GWAS		Triglyceride levels ( 32203549)	Alzheimer's disease ( 30636644) Blood urea nitrogen levels ( 29403010) Intraocular pressure ( 29617998 29785010 31959993) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Retinal detachment or retinal break ( 31816047) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Type 2 diabetes ( 25760438) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		16 interacting genes: APP CEBPB COIL CSNK2A1 CSNK2B E2F4 ERG GTF2B KBTBD8 MDM2 POLR1A PRKACA SRPK2 USP4 YWHAG YWHAQ	2 interacting genes: FBXL17 NOLC1
Entrez ID		9221	84541
HPRD ID		03864	18138
Ensembl ID		ENSG00000166197	ENSG00000163376
Uniprot IDs		B2RAU8 Q14978 Q96J17	Q8NFY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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