ATPAF2 and ZNF35

Data Source:
BioGRID (two hybrid)

		ATPAF2	ZNF35
Description		ATP synthase mitochondrial F1 complex assembly factor 2	zinc finger protein 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatogenesis Cellular Response To Retinoic Acid
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)	Bipolar disorder ( 31043756)
Interacting Genes		73 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	33 interacting genes: APP ATPAF2 CCDC130 CCDC136 CDC5L CDR2 CDR2L CEP70 CREB1 CWF19L2 EEF2KMT EXOC8 FSD2 GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOMEZ HOOK1 HOOK2 LZTS1 MAP3K20 MCC MTUS2 MYD88 NDEL1 PIBF1 PICK1 PNMA1 PRKAR1B TRAF2 ZBTB8A
Entrez ID		91647	7584
HPRD ID		10599	01920
Ensembl ID		ENSG00000171953	ENSG00000169981
Uniprot IDs		Q8N5M1	P13682
PDB IDs
Enriched GO Terms of Interacting Partners?
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