ATPAF2 and ATP5F1B

Data Source:
HPRD (two hybrid)

		ATPAF2	ATP5F1B
Description		ATP synthase mitochondrial F1 complex assembly factor 2	ATP synthase F1 subunit beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Nucleus Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Proton-transporting ATP Synthase, Catalytic Core Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Mitochondrial Membrane Mitochondrial Nucleoid Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding ATP Binding ATPase Activity MHC Class I Protein Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Angiogenesis Osteoblast Differentiation Generation Of Precursor Metabolites And Energy Lipid Metabolic Process ATP Biosynthetic Process Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Mitochondrion Organization Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Intracellular PH Cellular Response To Interleukin-7 Proton Transmembrane Transport
Pathways			Mitochondrial protein import Mitochondrial protein import Formation of ATP by chemiosmotic coupling Transcriptional activation of mitochondrial biogenesis Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Phenethyl Isothiocyanate
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		73 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	24 interacting genes: ANXA7 APOA1 ATP5F1C ATP5PF ATPAF1 ATPAF2 BYSL CDK4 CDKN1A FANCA GRB7 HMOX2 LNX2 PIN1 PLG PSME3 RPP14 SMN1 SUMO4 TERT TK1 TRIM55 TRIM63 YWHAG
Entrez ID		91647	506
HPRD ID		10599	00044
Ensembl ID		ENSG00000171953	ENSG00000110955
Uniprot IDs		Q8N5M1	P06576 V9HW31
PDB IDs
Enriched GO Terms of Interacting Partners?
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