SYNGR2 and C5AR2

Data Source:
BioGRID (two hybrid)

		SYNGR2	C5AR2
Description		synaptogyrin 2	complement component 5a receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Integral Component Of Membrane Synaptic Vesicle Membrane Neuromuscular Junction Extracellular Exosome	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell
	Molecular Function	Protein Binding	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Viral Process Regulated Exocytosis Synaptic Vesicle Membrane Organization	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Complement Activation Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis
Pathways			Peptide ligand-binding receptors Regulation of Complement cascade
Drugs
Diseases
GWAS		Adenocarcinoma ( 26732429) Lung cancer ( 26732429) Red blood cell count ( 32888494)
Interacting Genes		9 interacting genes: BDKRB2 C5AR2 CCR4 DRD2 F2RL1 FATE1 GPR35 LTB4R2 SCARA3	17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234
Entrez ID		9144	27202
HPRD ID		04891	17072
Ensembl ID		ENSG00000108639	ENSG00000134830
Uniprot IDs		A0A024R8T9 O43760	Q9P296
PDB IDs
Enriched GO Terms of Interacting Partners?
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