CNOT9 and GADD45B

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CNOT9	GADD45B
Description		CCR4-NOT transcription complex subunit 9	growth arrest and DNA damage inducible beta
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytosol Membrane CCR4-NOT Complex CCR4-NOT Core Complex Protein-containing Complex	Nucleus Cytoplasm
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Kinase Binding Protein Domain Specific Binding Nuclear Receptor Coactivator Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Sex Differentiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Gene Silencing By RNA Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated	Activation Of MAPKKK Activity Apoptotic Process Multicellular Organism Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade
Pathways		Deadenylation of mRNA Activation of anterior HOX genes in hindbrain development during early embryogenesis TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: AKT1 EGFR GADD45A GADD45B GADD45G GIGYF1 GIGYF2 GRB10 MESD MYB	15 interacting genes: CCNB1 CDK1 CDKN1A CNOT9 EFHC1 ESR1 GADD45G GADD45GIP1 MAP2K7 MAP3K4 MAP3K5 PCNA PPARA PPARD PPARG
Entrez ID		9125	4616
HPRD ID		08828	05382
Ensembl ID		ENSG00000144580	ENSG00000099860
Uniprot IDs		D5MQE1 Q92600	K7EPQ8 O75293
PDB IDs		2FV2 4CRU 4CRV 4CT6 4CT7 5LSW 5ONA 5ONB 6HOM 6HON
Enriched GO Terms of Interacting Partners?
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