USP6 and RAB33B

Data Source:
BioGRID (two hybrid)

		USP6	RAB33B
Description		ubiquitin specific peptidase 6	RAB33B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Plasma Membrane Recycling Endosome	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen
	Molecular Function	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity GTPase Activator Activity Protein Binding Calmodulin Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Intracellular Protein Transport Protein Deubiquitination Protein Phosphopantetheinylation Regulation Of Vesicle-mediated Transport Activation Of GTPase Activity	Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Autophagy Protein Transport Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER
Pathways			Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		18 interacting genes: ANKRD11 ANKRD44 APP ATXN7L3 CABP2 CALM2 CDC42 EXOSC8 JAK1 JUN MDFI MYL2 RAB33B RAC1 RIPPLY1 TFIP11 UBC ZNF76	12 interacting genes: ACVR1 ATG16L1 ATG16L2 ATG5 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6
Entrez ID		9098	83452
HPRD ID		06827	05808
Ensembl ID		ENSG00000129204	ENSG00000172007
Uniprot IDs		P35125	A0A494C0Z5 Q9H082
PDB IDs			6Y09 6ZAY
Enriched GO Terms of Interacting Partners?
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